Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL368334 | 0.83 | CYP3A4 (0.51) | MEN1KMT2AKDM4EAKR1C3CYP3A4 | |
| SCHEMBL11683148 | 0.81 | MEN1 (0.46) | MEN1KMT2AAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL6637645 | 0.80 | MEN1 (0.47) | MEN1KMT2AAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL11685413 | 0.79 | MEN1 (0.44) | MEN1KMT2AAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL10784757 | 0.78 | AKR1C3 (0.46) | MEN1KMT2AKDM4EAKR1C3CYP3A4 | |
| SCHEMBL924566 | 0.78 | MEN1 (0.49) | MEN1KMT2AAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL528920 | 0.78 | MEN1 (0.49) | MEN1KMT2AAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL5078093 | 0.77 | TDP1 (0.51) | MEN1KMT2AKDM4EAKR1C3CYP3A4 | |
| SCHEMBL2229690 | 0.76 | MEN1 (0.66) | MEN1KMT2AKDM4EAKR1C3CYP3A4 | |
| SCHEMBL1373611 | 0.75 | ALDH1A1 (0.50) | MEN1KMT2AAKR1C3CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050271692-A1 | Topical cosmetic compositions | COSMECEUTIC SOLUTIONS PTY. LTD. | 2005-12-08 | — | — | US | claimed |
| US-20050186141-A1 | Transdermal aerosol compositions | ACRUX DDS PTY LTD. | 2005-08-25 | — | — | US | claimed |
| EP-1534241-A1 | TRANSDERMAL AEROSOL COMPOSITIONS | Acrux DDS Pty Ltd (AU) | 2005-06-01 | — | — | EP | claimed |
| EP-1534214-A1 | TOPICAL COSMETIC COMPOSITIONS | Cosmeceutic Solutions Pty Ltd (AU) | 2005-06-01 | — | — | EP | claimed |
| WO-2004000275-A1 | TRANSDERMAL AEROSOL COMPOSITIONS | ACRUX DDS PTY LTD (AU) | 2003-12-31 | — | — | WO | claimed |
| WO-2004000242-A1 | TOPICAL COSMETIC COMPOSITIONS | COSMECEUTIC SOLUTIONS PTY LTD (AU) | 2003-12-31 | — | — | WO | claimed |
| US-20090098069-A1 | TRANSDERMAL, ALCOHOL-FREE, PHARMACEUTICAL COMPOSITIONS | DRUGTECH CORPORATION (US) | 2009-04-16 | — | — | US | disclosed |
| WO-2009036311-A1 | TRANSDERMAL, ALCOHOL-FREE, PHARMACEUTICAL COMPOSITIONS | DRUGTECH CORPORATION (US) | 2009-03-19 | — | — | WO | disclosed |
| US-20050271692-A1 | Topical cosmetic compositions | COSMECEUTIC SOLUTIONS PTY. LTD. | 2005-12-08 | — | — | US | disclosed |
| US-20050186141-A1 | Transdermal aerosol compositions | ACRUX DDS PTY LTD. | 2005-08-25 | — | — | US | disclosed |
| EP-1534241-A1 | TRANSDERMAL AEROSOL COMPOSITIONS | Acrux DDS Pty Ltd (AU) | 2005-06-01 | — | — | EP | disclosed |
| EP-1534214-A1 | TOPICAL COSMETIC COMPOSITIONS | Cosmeceutic Solutions Pty Ltd (AU) | 2005-06-01 | — | — | EP | disclosed |
| US-20050002868-A1 | Method of treatment of a female suffering from androgen insufficiency | ACRUX DDS PTY LTD. | 2005-01-06 | — | — | US | disclosed |
| WO-2004000242-A1 | TOPICAL COSMETIC COMPOSITIONS | COSMECEUTIC SOLUTIONS PTY LTD (AU) | 2003-12-31 | — | — | WO | disclosed |
| WO-2004000275-A1 | TRANSDERMAL AEROSOL COMPOSITIONS | ACRUX DDS PTY LTD (AU) | 2003-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050271692-A1 | Topical cosmetic compositions | CUTA, MITF, DSG1 | MEN1 2207/4885KMT2A 3646/4885KDM4E 2898/4885 |
| US-20050186141-A1 | Transdermal aerosol compositions | TSLP, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TRPA1 | MEN1 3884/4885KMT2A 4837/4885KDM4E 4381/4885 |
| US-20090098069-A1 | TRANSDERMAL, ALCOHOL-FREE, PHARMACEUTICAL COMPOSITIONS | NOTUM, TSLP, FAR1 | MEN1 1430/4885KMT2A 4201/4885KDM4E 1736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.