SCHEMBL3683777

SCHEMBL3683777

CC1=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc2C1[Zr](C)(C)([SiH3])(Cl)(Cl)C1C(C(C)C)=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6242940 0.91 BRD4 (0.32)
SCHEMBL21174676 0.90
SCHEMBL1022320 0.81
SCHEMBL7130806 0.81 KIF11 (0.35)
SCHEMBL7078536 0.79 EDNRB (0.30)
SCHEMBL6065619 0.78 BRD4 (0.32)
SCHEMBL5754513 0.78 GPR84 (0.31)
SCHEMBL27337650 0.78
SCHEMBL8830685 0.78 PDCD1 (0.32)
SCHEMBL26657371 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2173778-A1 CATALYST SYSTEM FOR POLYMERIZATION OF OLEFINIC MONOMERS, PROCESS FOR PREPARING POLYMERS AND POLYMERS PREPARED BY THE PROCESS Basell Polyolefine GmbH (DE) 2010-04-14 EP disclosed
WO-2009015804-A1 CATALYST SYSTEM FOR POLYMERIZATION OF OLEFINIC MONOMERS, PROCESS FOR PREPARING POLYMERS AND POLYMERS PREPARED BY THE PROCESS BASELL POLYOLEFINE GMBH (DE) 2009-02-05 WO disclosed