SCHEMBL3684084

SCHEMBL3684084

O=S(=O)(OSc1ccc(F)cc1)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
MAPK1 P28482 1/20 0.33
SOS1 Q07889 1/20 0.32
GAA P10253 1/20 0.31
CA2 P00918 2/20 0.31
HSD11B1 P28845 1/20 0.31
MMP2 P08253 2/20 0.31
CA1 P00915 1/20 0.31
MMP1 P03956 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3374912 0.84 CA2 (0.36) ALDH1A1MAPK1CA2CA1MMP8
SCHEMBL4249989 0.83 DNMT1 (0.40) ALDH1A1GAACA2CA1
SCHEMBL4263921 0.80 CA1 (0.40) ALDH1A1GAACA2HSD11B1CA1
SCHEMBL3683894 0.80 PKM (0.41) ALDH1A1GAACA2HSD11B1MMP2
SCHEMBL4575025 0.79 ALDH1A1 (0.37) ALDH1A1MAPK1GAACA2CA1
SCHEMBL6117483 0.79
SCHEMBL29048521 0.74 SMN1; SMN2 (0.55) ALDH1A1MAPK1GAACA2MMP2
SCHEMBL5114461 0.72 GLA (0.43) ALDH1A1GAACA2HSD11B1CA1
SCHEMBL776070 0.71 CXCR2 (0.45) SOS1CA2HSD11B1CA1
SCHEMBL7915292 0.70 CA12 (0.37) ALDH1A1MAPK1GAACA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2080750-B1 RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2020-07-29 EP disclosed
US-9897913-B2 Radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-02-20 US disclosed
EP-2487148-B1 CYCLIC COMPOUND, METHOD FOR PRODUCING SAME, RADIATION SENSITIVE COMPOSITION, AND METHOD FOR FORMING RESIST PATTERN MITSUBISHI GAS CHEMICAL CO (JP) 2014-12-31 EP disclosed
EP-2487148-A1 CYCLIC COMPOUND, METHOD FOR PRODUCING SAME, RADIATION SENSITIVE COMPOSITION, AND METHOD FOR FORMING RESIST PATTERN Mitsubishi Gas Chemical Company, Inc. (JP) 2012-08-15 EP disclosed
US-20100047709-A1 RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-02-25 US disclosed
EP-2080750-A1 RADIATION-SENSITIVE COMPOSITION Mitsubishi Gas Chemical Company, Inc. (JP) 2009-07-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100047709-A1 RADIATION-SENSITIVE COMPOSITION C1S, C9, RAD51 ALDH1A1 1078/4885MAPK1 3132/4885SOS1 743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.