SCHEMBL6003247

SCHEMBL6003247

O=S(F)(F)(F)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
BBOX1 O75936 1/20 0.33
EHMT2 Q96KQ7 1/20 0.33
EHMT1 Q9H9B1 1/20 0.33
ALDH1A1 P00352 5/20 0.32
TSHR P16473 2/20 0.30
DAO P14920 1/20 0.30
NAPRT Q6XQN6 1/20 0.30
ALOX15 P16050 1/20 0.30
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30
HTR6 P50406 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5042529 0.77 CES1 (0.33) BBOX1EHMT2EHMT1ALDH1A1TSHR
SCHEMBL8468773 0.73 BBOX1 (0.37) BBOX1EHMT2EHMT1ALDH1A1TSHR
SCHEMBL11285515 0.71 CA4 (0.35) ALDH1A1TSHRALOX15CES1
SCHEMBL776612 0.71 CYP2D6 (0.31) ALDH1A1TSHR
SCHEMBL10639940 0.69 NPSR1 (0.38) BBOX1EHMT2EHMT1ALDH1A1TSHR
SCHEMBL278265 0.69 TSHR (0.39) BBOX1EHMT2EHMT1ALDH1A1TSHR
SCHEMBL4632090 0.69 TSHR (0.35) BBOX1EHMT2EHMT1ALDH1A1TSHR
SCHEMBL3684648 0.69 TSHR (0.35) BBOX1EHMT2EHMT1ALDH1A1TSHR
SCHEMBL17963728 0.69 TSHR (0.35) BBOX1EHMT2EHMT1ALDH1A1TSHR
Benzene SCHEMBL28958130 0.69 TSHR (0.39) BBOX1EHMT2EHMT1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841429-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES Sumitomo Chemical Company Limited (JP) 2015-03-04 EP disclosed
EP-2841433-A1 TETRAZOLINONE COMPOUNDS AND ITS USE Sumitomo Chemical Company Limited (JP) 2015-03-04 EP disclosed
WO-2013162072-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-10-31 WO disclosed
WO-2013162077-A1 TETRAZOLINONE COMPOUNDS AND ITS USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-10-31 WO disclosed
EP-1678185-A1 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-07-12 EP disclosed
WO-2005042542-A1 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-05-12 WO disclosed