Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 9/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3657312 | 0.90 | NR3C1 (0.45) | NR3C1NR3C2PGR | |
| SCHEMBL3649794 | 0.80 | CHRM3 (0.37) | NR3C1NR3C2PGR | |
| SCHEMBL5800422 | 0.77 | NR3C1 (0.52) | NR3C1NR3C2PGR | |
| SCHEMBL3948025 | 0.74 | CYP3A4 (0.33) | — | |
| SCHEMBL5779282 | 0.72 | NR3C1 (0.44) | NR3C1NR3C2PGR | |
| SCHEMBL3680227 | 0.72 | KCNN4 (0.37) | NR3C1PGR | |
| SCHEMBL1634224 | 0.71 | NR3C2 (0.44) | NR3C1NR3C2PGR | |
| SCHEMBL8225347 | 0.69 | LMNA (0.47) | NR3C1NR3C2 | |
| SCHEMBL5777930 | 0.68 | NR3C1 (0.42) | NR3C1NR3C2PGR | |
| SCHEMBL13347574 | 0.66 | HTR2A (0.45) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190431-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST FOR TREATING OR CONTROLLING ANTERIOR-SEGMENT INFLAMMATION | Bausch & Lomb Incorporated (US) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009023471-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST FOR TREATING OR CONTROLLING ANTERIOR-SEGMENT INFLAMMATION | BAUSCH & LOMB INCORPORATED (US) | 2009-02-19 | — | — | WO | disclosed |