⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1137844 | 0.82 | — | — | |
| SCHEMBL6030016 | 0.81 | — | — | |
| SCHEMBL5372713 | 0.80 | OPRM1 (0.30) | — | |
| SCHEMBL1756558 | 0.80 | — | — | |
| SCHEMBL27849135 | 0.78 | — | — | |
| SCHEMBL27419105 | 0.77 | OPRM1 (0.37) | — | |
| SCHEMBL2830816 | 0.75 | — | — | |
| SCHEMBL27776297 | 0.74 | OPRM1 (0.39) | — | |
| SCHEMBL28190702 | 0.74 | — | — | |
| SCHEMBL27986342 | 0.73 | DNM1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834121-B2 | alkoxy-endcapped polysiloxane, epoxy-functional polysiloxane and an aminosilane curing agent; coating flexibility, hardness, impact resistance, corrosion resistance and/or chemical resistance with improved weatherability; fast-curing; without need for acrylates; reduced volatile organic content | PPG INDUSTRIES OHIO, INC. (US) | 2010-11-16 | — | — | US | disclosed |
| EP-2137274-A2 | SILICONE RESIN CONTAINING COATING COMPOSITIONS, RELATED COATED SUBSTRATES AND METHODS | PPG Industries Ohio, Inc. (US) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008121528-A2 | SILICONE RESIN CONTAINING COATING COMPOSITIONS, RELATED COATED SUBSTRATES AND METHODS | PPG INDUSTRIES OHIO, INC. (US) | 2008-10-09 | — | — | WO | disclosed |
| US-20070213492-A1 | SILICONE RESIN CONTAINING COATING COMPOSITIONS, RELATED COATED SUBSTRATES AND METHODS | PPG INDUSTRIES OHIO, INC. | 2007-09-13 | — | — | US | disclosed |