SCHEMBL3684985

SCHEMBL3684985

CCCCNCc1c(-c2cccc3c2Cc2ccccc2-3)ccc2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 2/20 0.37
KMT2A Q03164 2/20 0.36
POLB P06746 1/20 0.36
HTR7 P34969 1/20 0.35
PNMT P11086 1/20 0.35
BCHE P06276 1/20 0.35
ACHE P22303 1/20 0.35
BACE1 P56817 1/20 0.35
TSHR P16473 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
ALOX15 P16050 2/20 0.34
MEN1 O00255 1/20 0.34
S1PR4 O95977 1/20 0.34
S1PR5 Q9H228 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3679850 0.80 PNMT (0.38) KMT2AHTR7PNMTBCHEACHE
SCHEMBL3683729 0.79 PNMT (0.48) PNMTBCHEACHETSHRNPC1
SCHEMBL6652435 0.78 PTGS2 (0.38) SLC2A1KMT2APOLBTSHRNPSR1
SCHEMBL3679016 0.78 ALDH1A1 (0.39) KMT2APNMTBCHEACHEBACE1
SCHEMBL3672084 0.76 PNMT (0.43) HTR7PNMTBCHEACHEBACE1
SCHEMBL3199381 0.75 SLC2A1 (0.38) SLC2A1KMT2APOLBTSHRNPSR1
SCHEMBL3675927 0.75 MEN1 (0.38) KMT2AHTR7PNMTBCHEACHE
SCHEMBL3682556 0.75 PNMT (0.38) KMT2APOLBHTR7PNMTBCHE
SCHEMBL3205136 0.74 SLC2A1 (0.37) SLC2A1KMT2APOLBTSHRNPSR1
SCHEMBL3205017 0.74 SLC2A1 (0.38) SLC2A1KMT2APOLBTSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 SLC2A1 4359/4885KMT2A 2101/4885POLB 964/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 SLC2A1 4359/4885KMT2A 2101/4885POLB 964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.