Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.54 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.54 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.54 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.54 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.54 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.54 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.54 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.54 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.54 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.54 |
| ▸ | CYP4F8 | P98187 | 1/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370414 | 0.82 | CYP1A1 (0.51) | CYP3A4CYP1A2CYP2C19CYP1A1CYP2E1 | |
| SCHEMBL10915716 | 0.81 | IMPDH2 (0.59) | RAB9AALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL21783928 | 0.81 | KDM4E (0.51) | RAB9AALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL27771980 | 0.80 | KDM4E (0.52) | CYP1A2CYP1A1CYP1B1RAB9AALDH1A1 | |
| SCHEMBL21241033 | 0.79 | KDM4E (0.53) | RAB9AALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL26259901 | 0.79 | SMN1; SMN2 (0.49) | CYP1A2CYP1A1CYP1B1RAB9AALDH1A1 | |
| SCHEMBL9670054 | 0.78 | NPC1 (0.64) | CYP3A4RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL4895178 | 0.78 | ALDH1A1 (0.51) | CYP3A4CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL15517371 | 0.78 | MEN1 (0.62) | RAB9AALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL26259490 | 0.77 | RAB9A (0.47) | RAB9AALDH1A1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209449-B | Inhibitors of the kynurenine pathway | 库拉德夫制药私人有限公司 | 2019-02-01 | — | — | CN | claimed |
| US-9845317-B2 | Slow release of organoboronic acids in cross-coupling reactions | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-12-19 | — | — | US | disclosed |
| US-9845317-B2 | Slow release of organoboronic acids in cross-coupling reactions | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-12-19 | — | — | US | disclosed |
| US-20160376260-A1 | Slow Release of Organoboronic Acids in Cross-Coupling Reactions | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2016-12-29 | — | — | US | disclosed |
| US-9328102-B2 | Slow release of organoboronic acids in cross-coupling reactions | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-05-03 | — | — | US | disclosed |
| US-9328102-B2 | Slow release of organoboronic acids in cross-coupling reactions | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-05-03 | — | — | US | disclosed |
| US-20150246905-A1 | Slow Release of Organoboronic Acids in Cross-Coupling Reactions | NATIONAL SCIENCE FOUNDATION | 2015-09-03 | — | — | US | disclosed |
| US-20150246905-A1 | Slow Release of Organoboronic Acids in Cross-Coupling Reactions | NATIONAL SCIENCE FOUNDATION | 2015-09-03 | — | — | US | disclosed |
| US-9006463-B2 | Slow release of organoboronic acids in cross-coupling reactions | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-04-14 | — | — | US | disclosed |
| US-9006463-B2 | Slow release of organoboronic acids in cross-coupling reactions | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-04-14 | — | — | US | disclosed |
| US-20130317223-A1 | Slow Release of Organoboronic Acids in Cross-Coupling Reactions | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-11-28 | — | — | US | disclosed |
| US-8338601-B2 | Slow release of organoboronic acids in cross-coupling reactions | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-12-25 | — | — | US | disclosed |
| US-20100121062-A1 | Slow Release of Organoboronic Acids in Cross-Coupling Reactions | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-05-13 | — | — | US | disclosed |
| WO-2010036921-A2 | SLOW RELEASE OF ORGANOBORONIC ACIDS IN CROSS-COUPLING REACTIONS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246905-A1 | Slow Release of Organoboronic Acids in Cross-Coupling Reactions | BRS3, CD79B, GRB2 | CYP3A4 1856/4885CYP1A2 3196/4885CYP2C19 1458/4885 |
| US-20100121062-A1 | Slow Release of Organoboronic Acids in Cross-Coupling Reactions | BRS3, CD79B, GRB2 | CYP3A4 1856/4885CYP1A2 3196/4885CYP2C19 1458/4885 |
| US-20160376260-A1 | Slow Release of Organoboronic Acids in Cross-Coupling Reactions | BRS3, CD79B, GRB2 | CYP3A4 1856/4885CYP1A2 3196/4885CYP2C19 1458/4885 |
| US-20130317223-A1 | Slow Release of Organoboronic Acids in Cross-Coupling Reactions | BRS3, CD79B, GRB2 | CYP3A4 1856/4885CYP1A2 3196/4885CYP2C19 1458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.