Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.54 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3515333 | 0.83 | ESR1 (0.45) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL6130606 | 0.78 | ESR1 (0.48) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL25590621 | 0.77 | KIF11 (0.46) | KIF11CYP3A4LMNAHPGDTSHR | |
| SCHEMBL1719753 | 0.77 | ESR1 (0.54) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL27620452 | 0.76 | ESR1 (0.52) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL28512548 | 0.76 | ESR1 (0.52) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL14205568 | 0.75 | SRD5A2 (0.53) | TYRHPGDHSD17B10TSHRALDH1A1 | |
| SCHEMBL27878898 | 0.74 | ESR1 (0.50) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL320071 | 0.73 | ESR1 (0.48) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL11052001 | 0.73 | ESR1 (0.48) | ESR1ESR2KIF11CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700714-B2 | Optical element and achromatic lens | TEIJIN CHEMICALS, LTD. (JP) | 2010-04-20 | — | — | US | disclosed |
| US-20090143560-A1 | Optical Element and Achromatic Lens | TEIJIN CHEMICALS, LTD. | 2009-06-04 | — | — | US | disclosed |
| EP-1947131-A1 | OPTICAL DEVICE AND ACHROMATIC LENS | Teijin Chemicals, Ltd. (JP) | 2008-07-23 | — | — | EP | disclosed |