SCHEMBL320071

SCHEMBL320071

Oc1ccc(C(F)(F)C(F)(F)C(F)F)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 0.48
ESR2 Q92731 11/20 0.48
KIF11 P52732 1/20 0.46
CYP3A4 P08684 3/20 0.41
LMNA P02545 2/20 0.41
TYR P14679 2/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.41
AR P10275 1/20 0.41
TSHR P16473 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
HTR6 P50406 1/20 0.41
ESRRG P62508 1/20 0.41
SLC6A3 Q01959 1/20 0.41
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
CA12 O43570 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11052001 0.82 ESR1 (0.48) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL14722105 0.80 ESR1 (0.46) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL2868121 0.80 ESR1 (0.62) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL10578903 0.79 KCNN4 (0.35) CA1CA2RAB9ACA9
SCHEMBL3146868 0.77 KIF11 (0.46) KIF11CYP3A4LMNAHPGDTSHR
SCHEMBL5014138 0.77 CYP19A1 (0.39) LMNAHPGDTSHRMEN1MAPT
SCHEMBL6516942 0.77 CA1 (0.41) CA1CA2CA5ACA9
SCHEMBL10821951 0.77 TRPV4 (0.31)
SCHEMBL27620452 0.76 ESR1 (0.52) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL7870012 0.76 TSHR (0.48) KIF11LMNAHPGDTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271933-A Fluorine-containing epoxy coating design for inhibiting dust adsorption of direct-current basin-type insulator and preparation method thereof 华北电力大学 2024-07-02 CN claimed
CN-118185205-A Fluororubber sealing element resistant to high temperature and synthetic ester lubricating oil 北京橡胶工业研究设计院有限公司 2024-06-14 CN claimed
CN-117925057-B Preparation method of vinyl anti-corrosion resin coating 江苏金隆新材料有限公司 2024-05-31 CN claimed
CN-117925057-A Preparation method of vinyl anti-corrosion resin coating 江苏金隆新材料有限公司 2024-04-26 CN claimed
CN-115491023-A Thermoplastic foaming material, preparation method and application 德州市华祥新材料科技有限公司 2022-12-20 CN claimed
CN-118271933-A Fluorine-containing epoxy coating design for inhibiting dust adsorption of direct-current basin-type insulator and preparation method thereof 华北电力大学 2024-07-02 CN disclosed
CN-118185205-A Fluororubber sealing element resistant to high temperature and synthetic ester lubricating oil 北京橡胶工业研究设计院有限公司 2024-06-14 CN disclosed
CN-117925057-B Preparation method of vinyl anti-corrosion resin coating 江苏金隆新材料有限公司 2024-05-31 CN disclosed
CN-118027412-A Photo-alignment material 罗利克技术有限公司 2024-05-14 CN disclosed
CN-117925057-A Preparation method of vinyl anti-corrosion resin coating 江苏金隆新材料有限公司 2024-04-26 CN disclosed
EP-4347702-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS Wacker Chemie AG (DE) 2024-04-10 EP disclosed
US-20240018357-A1 AROMATIC POLYSULFONE, RESIN COMPOSITION, AND METHOD FOR PRODUCING AROMATIC POLYSULFONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-01-18 US disclosed
WO-1997045481-A1 FLUOROELASTOMER COMPOSITIONS CONTAINING ORGANO-ONIUM COMPOUNDS DYNEON LLC (US) 1997-12-04 WO disclosed
WO-1997045480-A1 FLUOROELASTOMER COMPOSITIONS DYNEON LLC (US) 1997-12-04 WO disclosed
WO-1997010193-A1 ETHYNYL SUBSTITUTED AROMATIC COMPOUNDS, SYNTHESIS, POLYMERS AND USES THEREOF THE DOW CHEMICAL COMPANY (US) 1997-03-20 WO disclosed
US-5582917-A CONCURRENT CURING FLUOROPOLYMER, POLYSILOXANE USING CURINGAGENT EASTMAN KODAK COMPANY (US) 1996-12-10 US disclosed
US-5286794-A Blends of polycarbonate containing fluorinated-bisphenol A and polyvinyl chloride ENICHEM S.P.A. (IT) 1994-02-15 US disclosed
EP-0576057-A1 Blends of polycarbonate containing fluorinated-bisphenol-A and polyvinyl chloride ENICHEM S.p.A. (IT) 1993-12-29 EP disclosed
EP-0254220-A1 Process for the preparation of 2.2-bisphenyl hexafluoropropane HOECHST AKTIENGESELLSCHAFT (DE) 1988-01-27 EP disclosed
US-4031692-A PICK RESISTANT POLYESTER TWIST FIBER INDUSTRIES, INC. (US) 1977-06-28 US disclosed