SCHEMBL3685907

SCHEMBL3685907

CCCCC(CC)COc1ccc(N)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.48
TSHR P16473 4/20 0.48
CYP3A4 P08684 6/20 0.44
ALDH1A1 P00352 4/20 0.44
CA2 P00918 1/20 0.44
APP P05067 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
LMNA P02545 3/20 0.40
MAPK1 P28482 1/20 0.40
HSD17B10 Q99714 1/20 0.40
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
ATM Q13315 1/20 0.39
SLC2A1 P11166 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28218032 0.92 TDP1 (0.44) TDP1TSHRCYP3A4ALDH1A1CA2
SCHEMBL1357035 0.91 ALDH1A1 (0.50) TDP1TSHRCYP3A4ALDH1A1CA2
SCHEMBL1356320 0.91 ALDH1A1 (0.50) TDP1TSHRCYP3A4ALDH1A1CA2
SCHEMBL20357876 0.86 CYP3A4 (0.47) TDP1TSHRCYP3A4ALDH1A1CA2
SCHEMBL10718066 0.86 TDP1 (0.59) TDP1TSHRCYP3A4ALDH1A1APP
SCHEMBL27153078 0.86 TDP1 (0.59) TDP1TSHRCYP3A4ALDH1A1APP
SCHEMBL28389543 0.85 TDP1 (0.57) TDP1TSHRCYP3A4CA2KDM4E
SCHEMBL21655075 0.85 CYP3A4 (0.43) TDP1CYP3A4ALDH1A1CA2L3MBTL1
SCHEMBL13454928 0.85 RAB9A (0.41) TDP1TSHRCYP3A4ALDH1A1CA2
SCHEMBL1822785 0.85 TDP1 (0.56) TDP1TSHRCYP3A4ALDH1A1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10752780-B2 Chromophores for photochromic compositions useful for three dimensional display applications NITTO DENKO CORPORATION (JP) 2020-08-25 US disclosed
CN-110073508-A Photoelectric conversion element 株式会社理光 2019-07-30 CN disclosed
EP-2009082-B1 Synergistic lubricating oil composition containing a mixture of a nitro-substituted diarylamine and a diarylamine CHEVRON ORONITE CO (US) 2017-08-30 EP disclosed
EP-2009082-B1 Synergistic lubricating oil composition containing a mixture of a nitro-substituted diarylamine and a diarylamine CHEVRON ORONITE CO (US) 2017-08-30 EP disclosed
US-20170044373-A1 CHROMOPHORES FOR PHOTOCHROMIC COMPOSITIONS USEFUL FOR THREE DIMENSIONAL DISPLAY APPLICATIONS NITTO DENKO CORPORATION (JP) 2017-02-16 US disclosed
US-20170044373-A1 CHROMOPHORES FOR PHOTOCHROMIC COMPOSITIONS USEFUL FOR THREE DIMENSIONAL DISPLAY APPLICATIONS NITTO DENKO CORPORATION (JP) 2017-02-16 US disclosed
WO-2015164390-A1 CHROMOPHORES FOR PHOTOCHROMIC COMPOSITIONS USEFUL FOR THREE DIMENSIONAL DISPLAY APPLICATIONS NITTO DENKO CORPORATION (JP) 2015-10-29 WO disclosed
US-7683017-B2 Synergistic lubricating oil composition containing a mixture of a nitro-substituted diarylamine and a diarylamine CHEVRON ORONITE COMPANY LLC (US) 2010-03-23 US disclosed
US-7683017-B2 Synergistic lubricating oil composition containing a mixture of a nitro-substituted diarylamine and a diarylamine CHEVRON ORONITE COMPANY LLC (US) 2010-03-23 US disclosed
US-7683017-B2 Synergistic lubricating oil composition containing a mixture of a nitro-substituted diarylamine and a diarylamine CHEVRON ORONITE COMPANY LLC (US) 2010-03-23 US disclosed
US-20040082472-A1 Recording material FUJI PHOTO FILM CO., LTD. 2004-04-29 US disclosed
US-20040048185-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD 2004-03-11 US disclosed
US-6573269-B1 Compounds for protecting surface of substrate from ultraviolet light ROCHE VITAMINS INC. 2003-06-03 US disclosed
WO-2003016292-A1 ULTRAVIOLET LIGHT ABSORBERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-02-27 WO disclosed
US-6329116-B1 CYAN COUPLER AND A DIAZONIUM SALT COMPOUND, EXCELLENT SHELF LIFE, IMAGE LIGHT-RESISTANCE, IMAGE FIXING, EXCELLENT HUE AND COLOR DENSITY, PREFERABLY MICROENCAPSULATED IN POLYURETHANE OR POLYUREA FUJI PHOTO FILM CO., LTD. (JP) 2001-12-11 US disclosed
CN-1289767-A Pyrimidine-2,4,6-trione compounds HOFFMANN LA ROCHE (CH) 2001-04-04 CN disclosed
EP-1081140-A2 Novel Pyrimidine-2,4,6-trione compounds F. HOFFMANN-LA ROCHE AG (CH) 2001-03-07 EP disclosed
US-4379819-A OIL SOLUBLE MONOAZO DYE CIBA-GEIGY AG (CH) 1983-04-12 US disclosed
US-4247337-A STABILIZED AGAINST FLOCCULATION BY ADDITION OF A PHENYLAMINOSULFONYL DERIVATIVE OF PHTHALOCYANINE CIBA-GEIGY CORPORATION (US) 1981-01-27 US disclosed
US-4199509-A FLOCCULATION RESISTANCE IN PAINTS AND PRINTING INKS CIBA-GEIGY CORPORATION (US) 1980-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10752780-B2 Chromophores for photochromic compositions useful for three dimensional display applications CRY1, RB1, BRD3 TDP1 2376/4885TSHR 4020/4885CYP3A4 1279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.