SCHEMBL3685920

SCHEMBL3685920

CC(C)(c1ccc(O)c(C(F)(F)F)c1)c1ccc(O)c(C(F)(F)F)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.57
KLF10 Q13118 1/20 0.50
ALOX15 P16050 3/20 0.47
ALOX12 P18054 1/20 0.47
RORC P51449 1/20 0.46
ESR2 Q92731 3/20 0.44
ALDH1A1 P00352 4/20 0.43
HSD17B10 Q99714 3/20 0.43
HPGD P15428 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
CYP3A4 P08684 2/20 0.43
AR P10275 2/20 0.43
TSHR P16473 1/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43
HTR6 P50406 1/20 0.43
ESRRG P62508 1/20 0.43
SLC6A3 Q01959 1/20 0.43
NR1I2 O75469 1/20 0.42
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12574818 0.93 ESR1 (0.71) ESR1KLF10ALOX15ALOX12RORC
SCHEMBL1599382 0.88 ALDH1A1 (0.59) ESR1ALOX15ALDH1A1HSD17B10HPGD
SCHEMBL863774 0.85 CES2 (0.55) ALDH1A1HSD17B10HPGDCYP3A4AR
SCHEMBL18606651 0.84 ESR1 (0.53) ESR1KLF10ALOX15ALOX12RORC
SCHEMBL13184020 0.83 ESR1 (0.41) ESR1KLF10ALOX15ALOX12RORC
SCHEMBL5397667 0.83 CES2 (0.44) ESR1ALOX15ESR2ALDH1A1HSD17B10
SCHEMBL122974 0.83 ALDH1A1 (0.61) ESR1KLF10ALOX15ALOX12RORC
SCHEMBL29352462 0.83 ALDH1A1 (0.61) ESR1KLF10ALOX15ALOX12RORC
SCHEMBL29377969 0.83 ALDH1A1 (0.61) ESR1KLF10ALOX15ALOX12RORC
SCHEMBL18399450 0.82 ESR1 (0.52) ESR1KLF10ALOX15ALOX12RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3431524-B1 POLYCARBONATE RESIN, METHOD FOR PRODUCING POLYCARBONATE RESIN, COATING LIQUID, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND ELECTROPHOTOGRAPHY DEVICE IDEMITSU KOSAN CO (JP) 2023-06-07 EP disclosed
US-11269263-B2 Bischloroformate composition, bischloroformate composition production method, bischloroformate composition-containing solution, polycarbonate resin, polycarbonate resin production method, coating liquid, electrophotographic photoreceptor, and electrophotographic device IDEMITSU KOSAN CO., LTD. (JP) 2022-03-08 US disclosed
US-10787541-B2 Polycarbonate resin, method for producing polycarbonate resin, coating liquid, electrophotographic photoreceptor, and electrophotography device IDEMITSU KOSAN CO., LTD. (JP) 2020-09-29 US disclosed
EP-3392235-B1 BISCHLOROFORMATE COMPOSITION, BISCHLOROFORMATE COMPOSITION PRODUCTION METHOD, BISCHLOROFORMATE COMPOSITION CONTAINING SOLUTION, POLYCARBONATE RESIN, POLYCARBONATE RESIN PRODUCTION METHOD, COATING LIQUID, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND ELECTROPHOTOGRAPHIC DEVICE IDEMITSU KOSAN CO (JP) 2020-04-29 EP disclosed
US-10241427-B2 Polycarbonate copolymer, coating solution, electrophotographic photoreceptor, and electric device IDEMITSU KOSAN CO., LTD. (JP) 2019-03-26 US disclosed
US-20190085120-A1 POLYCARBONATE RESIN, METHOD FOR PRODUCING POLYCARBONATE RESIN, COATING LIQUID, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND ELECTROPHOTOGRAPHY DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2019-03-21 US disclosed
EP-3431524-A1 POLYCARBONATE RESIN, METHOD FOR PRODUCING POLYCARBONATE RESIN, COATING LIQUID, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND ELECTROPHOTOGRAPHY DEVICE Idemitsu Kosan Co., Ltd (JP) 2019-01-23 EP disclosed
US-20180364598-A1 BISCHLOROFORMATE COMPOSITION, BISCHLOROFORMATE COMPOSITION PRODUCTION METHOD, BISCHLOROFORMATE COMPOSITION-CONTAINING SOLUTION, POLYCARBONATE RESIN, POLYCARBONATE RESIN PRODUCTION METHOD, COATING LIQUID, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND ELECTROPHOTOGRAPHIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-12-20 US disclosed
EP-3392235-A1 BISCHLOROFORMATE COMPOSITION, BISCHLOROFORMATE COMPOSITION PRODUCTION METHOD, BISCHLOROFORMATE COMPOSITION CONTAINING SOLUTION, POLYCARBONATE RESIN, POLYCARBONATE RESIN PRODUCTION METHOD, COATING LIQUID, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND ELECTROPHOTOGRAPHIC DEVICE Idemitsu Kosan Co., Ltd (JP) 2018-10-24 EP disclosed
US-20170075237-A1 POLYCARBONATE COPOLYMER, COATING SOLUTION, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND ELECTRIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-16 US disclosed
US-8846281-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2014-09-30 US disclosed
US-20110158683-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2011-06-30 US disclosed
US-7700714-B2 Optical element and achromatic lens TEIJIN CHEMICALS, LTD. (JP) 2010-04-20 US disclosed
US-7645547-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2010-01-12 US disclosed
US-7645547-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2010-01-12 US disclosed
US-20090143560-A1 Optical Element and Achromatic Lens TEIJIN CHEMICALS, LTD. 2009-06-04 US disclosed
US-20090029277-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-01-29 US disclosed
US-20090029277-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-01-29 US disclosed
EP-1947131-A1 OPTICAL DEVICE AND ACHROMATIC LENS Teijin Chemicals, Ltd. (JP) 2008-07-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180364598-A1 BISCHLOROFORMATE COMPOSITION, BISCHLOROFORMATE COMPOSITION PRODUCTION METHOD, BISCHLOROFORMATE COMPOSITION-CONTAINING SOLUTION, POLYCARBONATE RESIN, POLYCARBONATE RESIN PRODUCTION METHOD, COATING LIQUID, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND ELECTROPHOTOGRAPHIC DEVICE NR2E3, REV1, PBRM1 ESR1 412/4885KLF10 4742/4885ALOX15 1520/4885
US-11269263-B2 Bischloroformate composition, bischloroformate composition production method, bischloroformate composition-containing solution, polycarbonate resin, polycarbonate resin production method, coating liquid, electrophotographic photoreceptor, and electrophotographic device NR2E3, REV1, PBRM1 ESR1 412/4885KLF10 4742/4885ALOX15 1520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.