Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL1879779 | 0.89 | NPC1 (0.43) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| Benzo[C]Isoxazole SCHEMBL1833459 | 0.89 | RAB9A (0.43) | NPC1RAB9AALDH1A1MEN1LMNA | |
| Benzo[C]Isoxazole SCHEMBL27845401 | 0.89 | NPC1 (0.43) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| Benzo[C]Isoxazole SCHEMBL28208572 | 0.86 | RAB9A (0.42) | NPC1RAB9AALDH1A1MEN1LMNA | |
| Benzo[C]Isoxazole SCHEMBL22579004 | 0.83 | NPC1 (0.41) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL2491554 | 0.82 | GAA (0.46) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL2491479 | 0.82 | NPC1 (0.51) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| Benzo[C]Isoxazole SCHEMBL23045175 | 0.79 | NPC1 (0.38) | NPC1RAB9AALDH1A1ESR1ESR2 | |
| Benzo[C]Isoxazole SCHEMBL11231055 | 0.79 | RAB9A (0.41) | NPC1RAB9AALDH1A1LMNAMAPK1 | |
| Benzo[C]Isoxazole SCHEMBL18486460 | 0.79 | RAB9A (0.38) | NPC1RAB9AALDH1A1PDE10AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318995-B2 | Asymmetric pyrene derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2012-11-27 | — | — | US | disclosed |
| US-20100308718-A1 | ASYMMETRIC PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2010-12-09 | — | — | US | disclosed |
| US-7763761-B2 | Asymmetric pyrene derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-07-27 | — | — | US | disclosed |
| US-20070042220-A1 | Compound having spiro bond, material for luminescent coating formation and organic electroluminescence element including the same | IDEMITSU KOSAN CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1749809-A1 | ASYMMETRIC PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2007-02-07 | — | — | EP | disclosed |
| EP-1696708-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-20060154107-A1 | Asymmetric pyrene derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2006-07-13 | — | — | US | disclosed |
| US-20060051613-A1 | Material for organic electroluminescent device and organic electroluminescent device using same | IDEMITSU KOSAN CO., LTD. (JP) | 2006-03-09 | — | — | US | disclosed |
| EP-1623968-A1 | COMPOUND HAVING SPIRO BOND, MATERIAL FOR LUMINESCENT COATING FORMATION AND ORGANIC ELECTROLUMINESCENCE ELEMENT INCLUDING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2006-02-08 | — | — | EP | disclosed |
| EP-1595933-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2005-11-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100308718-A1 | ASYMMETRIC PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | ESR1, EBPL, JUP | NPC1 3856/4885RAB9A 3295/4885ALDH1A1 1078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.