Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 2/20 | 0.43 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluquinconazole SCHEMBL29422244 | 1.00 | TDO2 (0.43) | TDO2IDO2IDO1MPIPHOSPHO1 | |
| Fluquinconazole SCHEMBL21234 | 1.00 | TDO2 (0.43) | TDO2IDO2IDO1MPIPHOSPHO1 | |
| Fluquinconazole SCHEMBL29488449 | 1.00 | TDO2 (0.43) | TDO2IDO2IDO1MPIPHOSPHO1 | |
| SCHEMBL10518452 | 0.92 | KDM4E (0.39) | IDO1 | |
| Fluquinconazole SCHEMBL23174822 | 0.91 | IDO1 (0.37) | TDO2IDO2IDO1MPIPHOSPHO1 | |
| SCHEMBL16864750 | 0.90 | TDO2 (0.44) | TDO2IDO2IDO1 | |
| SCHEMBL10516150 | 0.88 | KDM4E (0.37) | IDO1 | |
| SCHEMBL10516516 | 0.88 | MEN1 (0.42) | TDO2IDO2IDO1 | |
| Fluquinconazole SCHEMBL2727515 | 0.87 | CYP3A4 (0.36) | — | |
| SCHEMBL15756732 | 0.86 | APAF1 (0.49) | TDO2IDO2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305161-A1 | COMBINATIONS OF FUNGICIDAL AZOLES AND PYRION COMPOUNDS | BOSSELAERS JAN PETER HENDRIK | 2010-12-02 | — | — | US | disclosed |
| US-7662748-B2 | Such as azaconazole, bromuconazole, and N,N',N'-tris(2-hydroxyethyl)-N-cocoalkyl-1,3-diamino-propane; kits; for protection of crops, plants, fruits, seeds, wood products, thatch, biodegradable material and textiles | JANSSEN PHARMACEUTICA, N.V. (BE) | 2010-02-16 | — | — | US | disclosed |
| US-20050080089-A1 | Formulations comprising triazoles and alkoxylated amines | AKZO NOBEL CHEMICALS BV (NL) | 2005-04-14 | — | — | US | disclosed |
| EP-1473996-A1 | FORMULATIONS COMPRISING TRIAZOLES AND ALKOXYLATED AMINES | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003065807-A1 | FORMULATIONS COMPRISING TRIAZOLES AND ALKOXYLATED AMINES | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080089-A1 | Formulations comprising triazoles and alkoxylated amines | ALKBH3, TYR, NAT1 | TDO2 35/4885IDO2 24/4885IDO1 10/4885 |
| US-20100305161-A1 | COMBINATIONS OF FUNGICIDAL AZOLES AND PYRION COMPOUNDS | PPOX, PNPO, CYP3A43 | TDO2 46/4885IDO2 33/4885IDO1 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.