Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGAV | P06756 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3686265 | 1.00 | ITGB3 (0.52) | ITGB3ITGAVCA2KMT2AGAA | |
| SCHEMBL1309029 | 0.91 | GAA (0.50) | KMT2AGAAMAPTRAB9AALDH1A1 | |
| SCHEMBL1309025 | 0.91 | GAA (0.50) | KMT2AGAAMAPTRAB9AALDH1A1 | |
| SCHEMBL1219646 | 0.89 | MEN1 (0.53) | CA2KMT2AFPR2MAPTRAB9A | |
| SCHEMBL1219647 | 0.89 | MEN1 (0.53) | CA2KMT2AFPR2MAPTRAB9A | |
| SCHEMBL6501552 | 0.86 | CA2 (0.58) | ITGB3CA2KMT2ARAB9APPARG | |
| SCHEMBL2747164 | 0.84 | KDM4A (0.57) | ITGB3MAPTPPARG | |
| SCHEMBL8718686 | 0.84 | ALDH1A1 (0.59) | ITGB3CA2KMT2AMAPTRAB9A | |
| SCHEMBL8904772 | 0.84 | ALDH1A1 (0.59) | ITGB3CA2KMT2AMAPTRAB9A | |
| SCHEMBL6921340 | 0.83 | GAA (0.58) | CA2KMT2AGAAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2352728-B1 | MELANOCORTIN RECEPTOR MODULATORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | GALDERMA RES & DEV (FR) | 2014-05-21 | — | — | EP | disclosed |
| WO-2010052255-A1 | MELANOCORTIN RECEPTOR MODULATORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-05-14 | — | — | WO | disclosed |