Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 10/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3648970 | 0.82 | — | — | |
| SCHEMBL3684692 | 0.79 | NR3C2 (0.43) | NR3C1NR3C2 | |
| SCHEMBL29114193 | 0.78 | HTR2A (0.40) | NR3C1NR3C2HTR2AHTR2CHTR2B | |
| SCHEMBL3652051 | 0.76 | NR3C2 (0.65) | NR3C1NR3C2PGR | |
| SCHEMBL10300148 | 0.74 | HTR2A (0.41) | NR3C1NR3C2HTR2AHTR2CHTR2B | |
| SCHEMBL3685002 | 0.72 | NR3C1 (0.49) | NR3C1NR3C2PGR | |
| SCHEMBL3949801 | 0.71 | AR (0.30) | NR3C1NR3C2 | |
| SCHEMBL13748809 | 0.70 | HTR2A (0.44) | HTR2AHTR2CHTR2B | |
| SCHEMBL3689211 | 0.69 | NR3C2 (0.46) | NR3C1NR3C2 | |
| SCHEMBL4442648 | 0.68 | NR3C1 (0.60) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190431-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST FOR TREATING OR CONTROLLING ANTERIOR-SEGMENT INFLAMMATION | Bausch & Lomb Incorporated (US) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009023471-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST FOR TREATING OR CONTROLLING ANTERIOR-SEGMENT INFLAMMATION | BAUSCH & LOMB INCORPORATED (US) | 2009-02-19 | — | — | WO | disclosed |