Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.30 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3648970 | 0.85 | — | — | |
| SCHEMBL24945815 | 0.72 | DAO (0.35) | PRKCZ | |
| SCHEMBL3686287 | 0.71 | NR3C1 (0.39) | NR3C1NR3C2 | |
| SCHEMBL3652962 | 0.71 | NR3C1 (0.51) | ARNR3C1NR3C2 | |
| SCHEMBL12804493 | 0.70 | TMPRSS4 (0.36) | — | |
| SCHEMBL4430202 | 0.65 | TAAR1 (0.44) | NR3C1NR3C2 | |
| SCHEMBL3655595 | 0.64 | PKM (0.41) | ARNR3C1NR3C2 | |
| SCHEMBL3658752 | 0.64 | NR3C1 (0.34) | NR3C1NR3C2 | |
| SCHEMBL4452422 | 0.63 | NR3C1 (0.49) | NR3C1NR3C2 | |
| SCHEMBL4460507 | 0.62 | NR3C1 (0.58) | NR3C1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051710-A2 | COMPOSITIONS AND METHODS FOR TREATING, REDUCING, AMELIORATING, OR ALLEVIATING POSTERIOR-SEGMENT OPHTHALMIC DISEASES | Bausch & Lomb Incorporated (US) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008021729-A2 | COMPOSITIONS AND METHODS FOR TREATING, REDUCING, AMELIORATING, OR ALLEVIATING POSTERIOR-SEGMENT OPHTHALMIC DISEASES | BAUSCH & LOMB INCORPORATED (US) | 2008-02-21 | — | — | WO | disclosed |