Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | JUN | P05412 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5915399 | 0.87 | ABCG2 (0.63) | ABCG2LMNAMAPTKDM4EATM | |
| SCHEMBL3687801 | 0.86 | TNFRSF1A (0.67) | ABCG2LMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL3684008 | 0.85 | PTPN1 (0.48) | ABCG2LMNAMAPTKDM4EATM | |
| SCHEMBL3688644 | 0.84 | ABCG2 (0.58) | ABCG2LMNAMAPTKDM4EATM | |
| SCHEMBL5915526 | 0.83 | ABCG2 (0.73) | ABCG2LMNAMAPTKDM4EATM | |
| SCHEMBL4845561 | 0.83 | ABCG2 (0.73) | ABCG2LMNAMAPTKDM4EATM | |
| SCHEMBL3686109 | 0.82 | MAOB (0.53) | ABCG2LMNAMAPTKDM4EATM | |
| SCHEMBL3692697 | 0.82 | MAOB (0.53) | ABCG2LMNAMAPTKDM4EATM | |
| SCHEMBL3682377 | 0.82 | PDE4A (0.56) | ABCG2LMNAMAPTKDM4EATM | |
| SCHEMBL3693773 | 0.81 | ABCG2 (0.67) | ABCG2MAPTL3MBTL1TNFRSF1APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | claimed |
| US-7642367-B2 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2010-01-05 | — | — | US | disclosed |
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | disclosed |