Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.84 |
| ▸ | MEN1 | O00255 | 6/20 | 0.84 |
| ▸ | PKM | P14618 | 2/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.84 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.83 |
| ▸ | IL1RN | P18510 | 1/20 | 0.83 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.83 |
| ▸ | GAA | P10253 | 3/20 | 0.77 |
| ▸ | GFER | P55789 | 1/20 | 0.68 |
| ▸ | CA12 | O43570 | 2/20 | 0.67 |
| ▸ | CA1 | P00915 | 2/20 | 0.67 |
| ▸ | CA2 | P00918 | 2/20 | 0.67 |
| ▸ | CA9 | Q16790 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | PGR | P06401 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | NAT1 | P18440 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001182 | 0.91 | KMT2A (1.00) | KMT2AMEN1PKMALDH1A1KEAP1 | |
| SCHEMBL25031372 | 0.91 | KEAP1 (1.00) | KMT2AMEN1PKMALDH1A1KEAP1 | |
| Phenyl(Phenylsulfonyl)Amine SCHEMBL114765 | 0.91 | KEAP1 (1.00) | KMT2AMEN1PKMALDH1A1KEAP1 | |
| SCHEMBL810795 | 0.91 | KMT2A (0.91) | KMT2AMEN1PKMALDH1A1KEAP1 | |
| Phenyl(Phenylsulfonyl)Amine SCHEMBL27503772 | 0.89 | KEAP1 (0.95) | KMT2AMEN1PKMALDH1A1KEAP1 | |
| Phenyl(Phenylsulfonyl)Amine SCHEMBL11513007 | 0.89 | KEAP1 (0.95) | KMT2AMEN1PKMALDH1A1KEAP1 | |
| Phenyl(Phenylsulfonyl)Amine SCHEMBL6399560 | 0.89 | KEAP1 (0.95) | KMT2AMEN1PKMALDH1A1KEAP1 | |
| SCHEMBL9479782 | 0.89 | MEN1 (0.67) | KMT2AMEN1PKMALDH1A1KEAP1 | |
| SCHEMBL92717 | 0.87 | KMT2A (1.00) | KMT2AMEN1PKMALDH1A1KEAP1 | |
| SCHEMBL1952693 | 0.87 | KMT2A (1.00) | KMT2AMEN1PKMALDH1A1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410150-B2 | Inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2013-04-02 | — | — | US | disclosed |
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK | 2010-04-29 | — | — | US | disclosed |
| WO-2008109991-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | CPT1A, CPT1B, CPT2 | KMT2A 662/4885MEN1 3665/4885PKM 1133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.