Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.95 |
| ▸ | IL1RN | P18510 | 1/20 | 0.95 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.95 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.87 |
| ▸ | MEN1 | O00255 | 3/20 | 0.87 |
| ▸ | PKM | P14618 | 2/20 | 0.87 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.87 |
| ▸ | CA12 | O43570 | 4/20 | 0.70 |
| ▸ | CA9 | Q16790 | 4/20 | 0.70 |
| ▸ | CA2 | P00918 | 3/20 | 0.70 |
| ▸ | CA1 | P00915 | 2/20 | 0.70 |
| ▸ | PGR | P06401 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | HTR6 | P50406 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25031372 | 0.98 | KEAP1 (1.00) | KEAP1IL1RNERAP1KMT2AMEN1 | |
| Phenyl(Phenylsulfonyl)Amine SCHEMBL114765 | 0.98 | KEAP1 (1.00) | KEAP1IL1RNERAP1KMT2AMEN1 | |
| Phenyl(Phenylsulfonyl)Amine SCHEMBL6399560 | 0.95 | KEAP1 (0.95) | KEAP1IL1RNERAP1KMT2AMEN1 | |
| Phenyl(Phenylsulfonyl)Amine SCHEMBL27503772 | 0.95 | KEAP1 (0.95) | KEAP1IL1RNERAP1KMT2AMEN1 | |
| SCHEMBL9001182 | 0.93 | KMT2A (1.00) | KEAP1IL1RNERAP1KMT2AMEN1 | |
| SCHEMBL810795 | 0.93 | KMT2A (0.91) | KEAP1IL1RNERAP1KMT2AMEN1 | |
| SCHEMBL3686387 | 0.89 | KMT2A (0.84) | KEAP1IL1RNERAP1KMT2AMEN1 | |
| SCHEMBL12640154 | 0.89 | KMT2A (0.84) | KEAP1IL1RNERAP1KMT2AMEN1 | |
| Phenyl(Phenylsulfonyl)Amine SCHEMBL6028137 | 0.87 | KEAP1 (0.80) | KEAP1IL1RNERAP1KMT2AMEN1 | |
| Phenyl(Phenylsulfonyl)Amine SCHEMBL11825113 | 0.87 | CA1 (0.89) | KEAP1IL1RNERAP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161524-A | INSECTICIDES, MITICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-17 | — | — | US | disclosed |
| US-4150155-A | INSECTICIDES, NEMATOCIDES, MITICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1979-04-17 | — | — | US | disclosed |
| US-4134979-A | INSECTICIDES, MITICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-01-16 | — | — | US | disclosed |