Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9859289 | 0.86 | CYP1A2 (0.49) | CA1CA2CYP2C9TSHRHIF1A | |
| SCHEMBL3691307 | 0.85 | PTGS1 (0.46) | PTGS1PTGS2ESR1ESR2CA2 | |
| SCHEMBL7972245 | 0.85 | ESR1 (0.54) | PTGS1PTGS2ESR1ESR2CA1 | |
| SCHEMBL25898409 | 0.85 | SHBG (0.57) | PTGS1PTGS2ESR1ESR2CYP2C9 | |
| SCHEMBL143803 | 0.84 | PTGS1 (0.47) | PTGS1PTGS2ESR1ESR2CA1 | |
| SCHEMBL25898412 | 0.82 | SHBG (0.39) | PTGS1PTGS2ESR1ESR2CYP2C9 | |
| SCHEMBL2618670 | 0.82 | ESR1 (0.57) | PTGS1PTGS2ESR1ESR2CA1 | |
| SCHEMBL25898410 | 0.81 | SHBG (0.53) | PTGS1PTGS2ESR1ESR2CYP2C9 | |
| SCHEMBL25898427 | 0.81 | CYP2C19 (0.51) | PTGS1PTGS2ESR1ESR2CYP2C9 | |
| SCHEMBL673998 | 0.81 | ESR1 (0.54) | PTGS1PTGS2ESR1ESR2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732562-B2 | Trisoxetane compound, production process and optical waveguide therewith | NITTO DENKO CORPORATION (JP) | 2010-06-08 | — | — | US | disclosed |
| EP-1842849-B1 | Trisoxetane compound, process for producing the same, and optical waveguide using the same | NITTO DENKO CORP (JP) | 2008-10-08 | — | — | EP | disclosed |
| US-20070237963-A1 | Trisoxetane compound, process for producing the same, and optical waveguide using the same | NITTO DENKO CORPORATION (JP) | 2007-10-11 | — | — | US | disclosed |
| EP-1842849-A1 | Trisoxetane compound, process for producing the same, and optical waveguide using the same | NITTO DENKO CORPORATION (JP) | 2007-10-10 | — | — | EP | disclosed |