Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25898410 | 0.97 | SHBG (0.53) | SHBGCYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL25898408 | 0.90 | SHBG (0.42) | SHBGCYP2C9CYP2C19KLF10KDM4E | |
| SCHEMBL25898412 | 0.85 | SHBG (0.39) | SHBGCYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL3686389 | 0.85 | PTGS1 (0.47) | SHBGCYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL25898427 | 0.84 | CYP2C19 (0.51) | SHBGCYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL25898413 | 0.82 | PRKCE (0.36) | SHBGCYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL25898430 | 0.81 | CYP2C19 (0.55) | SHBGCYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL28429147 | 0.76 | SHBG (0.69) | SHBGPTGS1PTGS2KDM4ECASP6 | |
| SCHEMBL9859289 | 0.76 | CYP1A2 (0.49) | CYP2C9CYP2C19CYP1A2CYP2D6KDM4E | |
| SCHEMBL25898411 | 0.76 | PRKCE (0.39) | CYP2C9CYP2C19PTGS2HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234905-A1 | NOVEL TRISPHENOL DERIVATIVE | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2023-07-27 | — | — | US | disclosed |
| US-20230234905-A1 | NOVEL TRISPHENOL DERIVATIVE | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234905-A1 | NOVEL TRISPHENOL DERIVATIVE | TTPA, CDK2AP2, CDKL2 | SHBG 131/4885CYP2C9 1486/4885CYP2C19 1012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.