Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2029120 | 0.89 | ESR1 (0.54) | ESR1ESR2CA2CA1CYP2C9 | |
| SCHEMBL5953180 | 0.88 | CYP2C9 (0.62) | ESR1ESR2CA2CA1CYP2C9 | |
| SCHEMBL7101111 | 0.88 | ESR1 (0.53) | ESR1ESR2CYP2C9TSHRHIF1A | |
| SCHEMBL5873699 | 0.86 | ESR1 (0.57) | ESR1ESR2ARTDP1 | |
| SCHEMBL673998 | 0.85 | ESR1 (0.54) | ESR1ESR2CA2CA1CYP2C9 | |
| SCHEMBL7969192 | 0.85 | TSHR (0.59) | ESR1ESR2CA2CA1CYP2C9 | |
| SCHEMBL7970288 | 0.85 | CYP2C9 (0.59) | ESR1ESR2CA2CA1CYP2C9 | |
| SCHEMBL2031385 | 0.85 | ESR1 (0.50) | ESR1ESR2CA2CA1CYP2C9 | |
| SCHEMBL3686389 | 0.85 | PTGS1 (0.47) | ESR1ESR2CA2CA1CYP2C9 | |
| SCHEMBL6431647 | 0.83 | ESR1 (0.48) | ESR1ESR2CA2CA1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268462-B1 | Branched polycarbonate resin and process for the preparation thereof | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2001-07-31 | — | — | US | disclosed |
| EP-1008608-A1 | BRANCHED POLYCARBONATE RESIN AND PROCESS FOR THE PREPARATION THEREOF | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2000-06-14 | — | — | EP | disclosed |
| US-4415725-A | MOLDING MATERIALS; BLOW MOLDING; BOTTLES; FILMS | GENERAL ELECTRIC CO. (US) | 1983-11-15 | — | — | US | disclosed |