Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL283280 | 0.79 | ALDH1A1 (0.52) | HSD17B10HTTNPC1RAB9AALOX15 | |
| SCHEMBL12536873 | 0.79 | ALDH1A1 (0.44) | HSD17B10HTTNPC1RAB9ATP53 | |
| SCHEMBL13800945 | 0.79 | HSD17B10 (0.40) | HSD17B10HTTNPC1RAB9ATP53 | |
| SCHEMBL18352875 | 0.78 | CES1 (0.42) | HSD17B10HTTTP53KMT2AMEN1 | |
| SCHEMBL12536605 | 0.78 | ALDH1A1 (0.44) | HSD17B10HTTNPC1RAB9ATP53 | |
| SCHEMBL3910072 | 0.78 | — | — | |
| SCHEMBL7453197 | 0.77 | SMN1; SMN2 (0.43) | HSD17B10NPC1RAB9ATP53KMT2A | |
| SCHEMBL13800984 | 0.76 | MAPT (0.44) | HSD17B10HTTNPC1RAB9ATP53 | |
| SCHEMBL952705 | 0.75 | HSD17B10 (0.43) | HSD17B10HTTTP53ALOX15KMT2A | |
| SCHEMBL27264408 | 0.75 | TSHR (0.42) | HSD17B10HTTNPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025035108-A2 | INHIBITORS OF PARG | ARASE THERAPEUTICS INC. (US) | 2025-02-13 | — | — | WO | disclosed |
| WO-2024245310-A1 | THIAZOLYL OR THIADIAZOLYL AMIDES DERIVATIVES AND USE THEREOF | NINGBO NEWBAY TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2024-12-05 | — | — | WO | disclosed |
| US-11530205-B2 | GLP-1 receptor modulators | RECEPTOS LLC (US) | 2022-12-20 | — | — | US | disclosed |
| EP-3615524-B1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC (US) | 2022-11-09 | — | — | EP | disclosed |
| WO-2022095989-A1 | P300 INHIBITORS AND USE THEREOF IN MEDICINE | 贝达药业股份有限公司 | 2022-05-12 | — | — | WO | disclosed |
| US-20210371409-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2021-12-02 | — | — | US | disclosed |
| EP-3615524-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | Celgene International II Sàrl (CH) | 2020-03-04 | — | — | EP | disclosed |
| WO-2018200833-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | CELGENE INTERNATIONAL II SARL (CH) | 2018-11-01 | — | — | WO | disclosed |
| US-9532989-B2 | Oxadiazolo[3,2-A]pyrimidines and thiadiazolo[3,2-A]pyrimidines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2017-01-03 | — | — | US | disclosed |
| US-20150374697-A1 | ORGANIC COMPOUNDS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2015-12-31 | — | — | US | disclosed |
| US-9066948-B2 | Oxadiazolo[3,2-a]pyrimidines and thiadiazolo[3,2-a]pyrimidines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2015-06-30 | — | — | US | disclosed |
| US-20130251761-A1 | ORGANIC COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-09-26 | — | — | US | disclosed |
| EP-2593106-A1 | ORGANIC COMPOUNDS | Rockefeller University (US) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012009688-A1 | ORGANIC COMPOUNDS | ROCKEFELLER UNIVERSITY (US) | 2012-01-19 | — | — | WO | disclosed |
| WO-1999031096-A1 | PIPERAZINE DERIVATIVES USEFUL AS HYPOGLYCEMIC AGENTS | SHAMAN PHARMACEUTICALS, INC. (US) | 1999-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210371409-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, GCGR | HSD17B10 3262/4885HTT 1821/4885NPC1 2298/4885 |
| US-11530205-B2 | GLP-1 receptor modulators | GLP1R, GIPR, GCGR | HSD17B10 3431/4885HTT 1726/4885NPC1 2088/4885 |
| US-20150374697-A1 | ORGANIC COMPOUNDS | PLAT, ICAM1, VCAM1 | HSD17B10 1526/4885HTT 1286/4885NPC1 601/4885 |
| US-20130251761-A1 | ORGANIC COMPOUNDS | PLAT, ICAM1, VCAM1 | HSD17B10 1526/4885HTT 1286/4885NPC1 601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.