Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.56 |
| ▸ | ALDH1A3 | P47895 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694793 | 0.89 | ALDH1A1 (0.57) | ALDH1A1ALDH1A3MAPTMEN1KMT2A | |
| SCHEMBL236991 | 0.83 | ALDH1A3 (0.66) | ALDH1A1ALDH1A3MAPTMEN1KMT2A | |
| SCHEMBL19212190 | 0.81 | ALDH1A3 (0.46) | ALDH1A1ALDH1A3MAPTMEN1KMT2A | |
| SCHEMBL27899384 | 0.81 | ALDH1A1 (0.59) | ALDH1A1ALDH1A3MAPTMEN1KMT2A | |
| SCHEMBL19137930 | 0.81 | ALDH1A1 (0.73) | ALDH1A1ALDH1A3MAPTMEN1KMT2A | |
| SCHEMBL5179998 | 0.81 | ALDH1A3 (0.69) | ALDH1A1ALDH1A3MAPTGAASMN1; SMN2 | |
| SCHEMBL29707378 | 0.78 | LMNA (0.47) | ALDH1A1ALDH1A3MAPTMEN1KMT2A | |
| SCHEMBL17756944 | 0.78 | LMNA (0.47) | ALDH1A1ALDH1A3MAPTMEN1KMT2A | |
| SCHEMBL27899382 | 0.77 | ALDH1A1 (0.51) | ALDH1A1ALDH1A3MAPTMEN1KMT2A | |
| SCHEMBL27899339 | 0.77 | ALDH1A1 (0.54) | ALDH1A1ALDH1A3MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642367-B2 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2010-01-05 | — | — | US | disclosed |
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | disclosed |
| EP-1506158-A2 | DIAMINO-FUNCTIONAL CHALCONES | Lica Pharmaceuticals A/S (DK) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097576-A2 | DIAMINO-FUNCTIONAL CHALCONES | LICA PHARMACEUTICALS A/S (DK) | 2003-11-27 | — | — | WO | disclosed |