Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | TNF | P01375 | 3/20 | 0.34 |
| ▸ | LITAF | Q99732 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3699154 | 0.79 | HTR1A (0.36) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL3686475 | 0.76 | KCNH2 (0.40) | HTR1AADRA1DADRA1AADRA1BPDE10A | |
| SCHEMBL3698422 | 0.74 | KCNH2 (0.43) | — | |
| SCHEMBL3698211 | 0.74 | KCNA3 (0.36) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL16964453 | 0.73 | HTR1A (0.60) | HTR1AADRA1DADRA1AADRA1BPDE10A | |
| SCHEMBL3687251 | 0.72 | HTR1A (0.31) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL3688086 | 0.71 | HTR1A (0.42) | HTR1AADRA1DADRA1AADRA1BPDE10A | |
| SCHEMBL3692453 | 0.71 | HTR1A (0.49) | HTR1AADRA1DADRA1AADRA1BENPP1 | |
| SCHEMBL16106422 | 0.70 | HTR1A (0.54) | HTR1AADRA1DADRA1AADRA1BPDE10A | |
| SCHEMBL3694763 | 0.70 | HTR1A (0.45) | HTR1AADRA1DADRA1AADRA1BPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2239260-A1 | Novel compounds with antibacterial activity | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2010-10-13 | — | — | EP | disclosed |
| EP-1551829-A2 | NOVEL COMPOUNDS WITH ANTIBACTERIAL ACTIVITY | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004035569-A2 | NOVEL COMPOUNDS WITH ANTIBACTERIAL ACTIVITY | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2004-04-29 | — | — | WO | disclosed |