Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5649014 | 0.84 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL3688398 | 0.73 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL3686478 | 0.72 | HTR1A (0.43) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL3686475 | 0.71 | KCNH2 (0.40) | HTR1AADRA1DADRA1AADRA1BKCNH2 | |
| SCHEMBL3699154 | 0.71 | HTR1A (0.36) | HTR1AADRA1DADRA1AADRA1BKCNH2 | |
| SCHEMBL3687395 | 0.70 | — | — | |
| SCHEMBL6219493 | 0.62 | KCNH2 (0.45) | HTR1AADRA1DADRA1AADRA1BKCNH2 | |
| SCHEMBL3698211 | 0.61 | KCNA3 (0.36) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL3688086 | 0.61 | HTR1A (0.42) | HTR1AADRA1DADRA1AADRA1BKCNH2 | |
| SCHEMBL3689424 | 0.61 | HTR1A (0.44) | HTR1AADRA1DADRA1AADRA1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2239260-A1 | Novel compounds with antibacterial activity | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2010-10-13 | — | — | EP | disclosed |
| EP-1551829-A2 | NOVEL COMPOUNDS WITH ANTIBACTERIAL ACTIVITY | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004035569-A2 | NOVEL COMPOUNDS WITH ANTIBACTERIAL ACTIVITY | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2004-04-29 | — | — | WO | disclosed |