Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 1/20 | 0.30 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3682787 | 0.87 | SLC2A1 (0.41) | CMA1PFKFB3 | |
| SCHEMBL13508397 | 0.80 | PER2 (0.40) | CMA1PER2PFKFB3 | |
| SCHEMBL14338976 | 0.80 | PER2 (0.40) | CMA1PER2PFKFB3 | |
| SCHEMBL3680982 | 0.79 | CMA1 (0.33) | CA2CMA1PFKFB3 | |
| SCHEMBL3686683 | 0.79 | HTR6 (0.34) | CA2CMA1PFKFB3 | |
| SCHEMBL3691886 | 0.77 | CMA1 (0.32) | CA2CMA1PFKFB3 | |
| SCHEMBL3681157 | 0.72 | PPARD (0.39) | — | |
| SCHEMBL3687742 | 0.69 | SLC2A1 (0.44) | CMA1PFKFB3 | |
| SCHEMBL3687739 | 0.69 | SLC2A1 (0.44) | CMA1PFKFB3 | |
| SCHEMBL3683465 | 0.69 | LMNA (0.34) | CMA1PFKFB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| US-20060217433-A1 | Sulfonamide derivatives as ppar modulators | ELI LILLY AND COMPANY (US) | 2006-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060217433-A1 | Sulfonamide derivatives as ppar modulators | PPARD, PPARA, PPARG | CA2 1679/4885CMA1 4529/4885PER2 782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.