Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3687211 | 0.88 | LMNA (0.46) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3691644 | 0.82 | CYP1B1 (0.46) | MAPTMEN1KMT2ATLR9CYP1A1 | |
| SCHEMBL3687806 | 0.80 | MAPT (0.47) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3686571 | 0.80 | MAPT (0.47) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3691515 | 0.79 | MAPT (0.56) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL13464612 | 0.79 | CYP1B1 (0.52) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3685711 | 0.79 | BCHE (0.58) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3687525 | 0.77 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL657764 | 0.76 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL657763 | 0.76 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | claimed |
| US-7642367-B2 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2010-01-05 | — | — | US | disclosed |
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | disclosed |