Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30205679 | 0.86 | CES2 (0.43) | ALDH1A1CES2CES1KDM4ESMN1; SMN2 | |
| SCHEMBL30205664 | 0.86 | CES2 (0.43) | ALDH1A1CES2CES1KDM4ESMN1; SMN2 | |
| SCHEMBL30205644 | 0.86 | CES2 (0.43) | ALDH1A1CES2CES1KDM4ESMN1; SMN2 | |
| SCHEMBL30205654 | 0.86 | CES2 (0.43) | ALDH1A1CES2CES1KDM4ESMN1; SMN2 | |
| SCHEMBL18386266 | 0.83 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL3689471 | 0.82 | ALDH1A1 (0.33) | ALDH1A1CES2CES1KDM4ESMN1; SMN2 | |
| SCHEMBL3682761 | 0.80 | LMNA (0.34) | ALDH1A1CES2CES1KDM4ESMN1; SMN2 | |
| SCHEMBL3684598 | 0.79 | LMNA (0.37) | ALDH1A1CES2CES1 | |
| SCHEMBL333892 | 0.73 | CYP2C19 (0.34) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4461505 | 0.71 | LMNA (0.37) | ALDH1A1CES2CES1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7847000-B2 | Silica-filled elastomeric compounds | LANXESS INC. (CA) | 2010-12-07 | — | — | US | claimed |
| EP-1680469-B1 | SILICA-FILLED ELASTOMERIC COMPOUNDS | LANXESS INC (CA) | 2009-01-07 | — | — | EP | claimed |
| EP-1680469-A4 | SILICA-FILLED ELASTOMERIC COMPOUNDS | LANXESS INC (CA) | 2007-09-05 | — | — | EP | claimed |
| JP-2007509209-A | — | — | 2007-04-12 | — | — | JP | claimed |
| US-20060293423-A1 | Silica-filled elastomeric compounds | LANXESS INC. (CA) | 2006-12-28 | — | — | US | claimed |
| EP-1680469-A1 | SILICA-FILLED ELASTOMERIC COMPOUNDS | Lanxess Inc. (CA) | 2006-07-19 | — | — | EP | claimed |
| WO-2005040272-A1 | SILICA-FILLED ELASTOMERIC COMPOUNDS | LANXESS INC. (CA) | 2005-05-06 | — | — | WO | claimed |
| US-7847000-B2 | Silica-filled elastomeric compounds | LANXESS INC. (CA) | 2010-12-07 | — | — | US | disclosed |
| EP-1680469-B1 | SILICA-FILLED ELASTOMERIC COMPOUNDS | LANXESS INC (CA) | 2009-01-07 | — | — | EP | disclosed |
| US-20080242771-A1 | Butyl Rubber Composition for Tire Treads | LANXESS INC. (CA) | 2008-10-02 | — | — | US | disclosed |
| EP-1680469-A4 | SILICA-FILLED ELASTOMERIC COMPOUNDS | LANXESS INC (CA) | 2007-09-05 | — | — | EP | disclosed |
| US-20060293423-A1 | Silica-filled elastomeric compounds | LANXESS INC. (CA) | 2006-12-28 | — | — | US | disclosed |
| EP-1694764-A1 | BUTYL RUBBER COMPOSITION FOR TIRE TREADS | Lanxess Inc. (CA) | 2006-08-30 | — | — | EP | disclosed |
| EP-1680469-A1 | SILICA-FILLED ELASTOMERIC COMPOUNDS | Lanxess Inc. (CA) | 2006-07-19 | — | — | EP | disclosed |
| WO-2005056664-A1 | BUTYL RUBBER COMPOSITION FOR TIRE TREADS | LANXESS INC. (CA) | 2005-06-23 | — | — | WO | disclosed |
| WO-2005040272-A1 | SILICA-FILLED ELASTOMERIC COMPOUNDS | LANXESS INC. (CA) | 2005-05-06 | — | — | WO | disclosed |