Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786559 | 0.78 | KDM4E (0.50) | LMNAALDH1A1MAPK1ALOX15HSD17B10 | |
| SCHEMBL24982899 | 0.78 | MAPT (0.75) | LMNATDP1ALDH1A1MAPK1ALOX15 | |
| SCHEMBL17482350 | 0.76 | TSHR (0.61) | LMNATDP1ALDH1A1MAPK1ALOX15 | |
| SCHEMBL8685928 | 0.76 | ALDH1A1 (0.64) | LMNATDP1ALDH1A1MAPK1ALOX15 | |
| SCHEMBL8685441 | 0.75 | TBXAS1 (0.70) | ALDH1A1MAPK1TBXAS1CYP19A1POLB | |
| SCHEMBL10370478 | 0.75 | TBXAS1 (1.00) | LMNAALDH1A1MAPK1TBXAS1MEN1 | |
| SCHEMBL8580210 | 0.75 | TBXAS1 (0.79) | LMNATDP1ALDH1A1MAPK1ALOX15 | |
| SCHEMBL31518372 | 0.75 | TBXAS1 (0.58) | LMNATDP1ALDH1A1TBXAS1POLB | |
| SCHEMBL501977 | 0.75 | TBXAS1 (0.58) | LMNATDP1ALDH1A1TBXAS1POLB | |
| SCHEMBL10999593 | 0.75 | POLB (0.72) | LMNATDP1TBXAS1CYP19A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | claimed |
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | disclosed |