SCHEMBL368692

SCHEMBL368692

CCCC(N)C/N=N/c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPT P10636 1/20 0.35
PKM P14618 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
AOC3 Q16853 2/20 0.34
TSHR P16473 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
CYP1A2 P05177 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1B1 Q16678 1/20 0.33
SIGMAR1 Q99720 2/20 0.33
NOS3 P29474 3/20 0.33
NOS1 P29475 3/20 0.33
NOS2 P35228 2/20 0.33
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL368694 0.76 EPHX1 (0.47) ALDH1A1MEN1KMT2AMAPTPKM
SCHEMBL10613600 0.72 ALDH1A1 (0.48) ALDH1A1MEN1KMT2AMAPTPKM
SCHEMBL10613589 0.72 ALDH1A1 (0.48) ALDH1A1MEN1KMT2AMAPTPKM
SCHEMBL368693 0.72 NOS3 (0.38) ALDH1A1MEN1KMT2AMAPTPKM
SCHEMBL28528303 0.70 CSNK1E (0.43) ALDH1A1MEN1KMT2ACSNK1E
SCHEMBL27977724 0.70 ALDH1A1 (0.50) ALDH1A1MEN1KMT2AMAPTPKM
SCHEMBL12198798 0.70 ALDH1A1 (0.50) ALDH1A1MEN1KMT2AMAPTPKM
SCHEMBL13715786 0.69 ALDH1A1 (0.55) ALDH1A1MEN1KMT2AMAPTPKM
Azobenzene SCHEMBL15261802 0.69 ALDH1A1 (0.71) ALDH1A1MEN1KMT2AMAPTPKM
SCHEMBL14471186 0.67 EPHX1 (0.67) SIGMAR1EPHX1MAOACSNK1E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107573326-B Novel benzotriazole derivative and organic electroluminescent device using the same 保土谷化学工业株式会社 2024-03-15 CN disclosed
EP-3432688-B1 ORGANIC ELECTROLUMINESCENCE ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2023-12-20 EP disclosed
CN-112079814-B Benzotriazole derivative and organic electroluminescent device 保土谷化学工业株式会社 2023-11-07 CN disclosed
US-11056653-B2 Organic electroluminescence device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-07-06 US disclosed
CN-112079814-A Benzotriazole derivative and organic electroluminescent device 保土谷化学工业株式会社 2020-12-15 CN disclosed
US-20200328353-A1 Organic Electroluminescence Device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-10-15 US disclosed
EP-2767534-B1 NEW BENZOTRIAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT IN WHICH SAID DERIVATIVE IS USED HODOGAYA CHEMICAL CO LTD (JP) 2020-06-03 EP disclosed
EP-3432688-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2019-01-23 EP disclosed
EP-2409974-B1 COMPOUND HAVING BENZOTRIAZOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2018-04-25 EP disclosed
US-9842999-B2 Benzotriazole derivative and an organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2017-12-12 US disclosed
US-20160164001-A1 A BENZOTRIAZOLE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2016-06-09 US disclosed
EP-3029034-A1 BENZOTRIAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2016-06-08 EP disclosed
US-9123897-B2 Benzotriazole derivatives and organic electroluminescent devices using the derivatives HODOGAYA CHEMICAL CO., LTD. (JP) 2015-09-01 US disclosed
US-9005776-B2 Compound having benzotriazole ring structure and organic electroluminescent element HODOGAYA CHEMICAL CO., LTD. (JP) 2015-04-14 US disclosed
US-20140374721-A1 NOVEL BENZOTRIAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE DERIVATIVES HODOGAYA CHEMICAL CO., LTD (JP) 2014-12-25 US disclosed
EP-2767534-A1 NEW BENZOTRIAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT IN WHICH SAID DERIVATIVE IS USED Hodogaya Chemical Co., Ltd. (JP) 2014-08-20 EP disclosed
EP-2409974-A1 COMPOUND HAVING BENZOTRIAZOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2012-01-25 EP disclosed
US-20120012831-A1 COMPOUND HAVING BENZOTRIAZOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENT ELEMENT SHINSHU UNIVERSITY (JP) 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160164001-A1 A BENZOTRIAZOLE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE AHR, ARNT, NAT1 ALDH1A1 215/4885MEN1 2403/4885KMT2A 142/4885
US-20120012831-A1 COMPOUND HAVING BENZOTRIAZOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENT ELEMENT BRD4, ARNT, MLLT1 ALDH1A1 1915/4885MEN1 2217/4885KMT2A 154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.