Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 7/20 | 0.41 |
| ▸ | PFKFB3 | Q16875 | 6/20 | 0.41 |
| ▸ | PFKFB4 | Q16877 | 6/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3686803 | 0.85 | KDM4E (0.46) | NPSR1L3MBTL1KDM4ECMA1PFKFB3 | |
| SCHEMBL2226181 | 0.81 | NPSR1 (0.60) | NPSR1L3MBTL1CMA1PFKFB3PFKFB4 | |
| Hydrochloric Acid SCHEMBL6712744 | 0.79 | NPSR1 (0.59) | NPSR1L3MBTL1CMA1PFKFB3PFKFB4 | |
| SCHEMBL3956129 | 0.78 | NPSR1 (0.45) | NPSR1L3MBTL1KDM4ECMA1PFKFB3 | |
| SCHEMBL3690124 | 0.78 | L3MBTL1 (0.45) | NPSR1L3MBTL1KDM4ECMA1PFKFB3 | |
| SCHEMBL3692731 | 0.77 | NPSR1 (0.41) | NPSR1L3MBTL1KDM4ECMA1PFKFB3 | |
| SCHEMBL19299978 | 0.72 | MCL1 (0.57) | KDM4EPFKFB3PFKFB4RNASEH1KEAP1 | |
| SCHEMBL3947527 | 0.72 | HTR6 (0.45) | NPSR1L3MBTL1KDM4ECMA1PFKFB3 | |
| SCHEMBL4658351 | 0.71 | NPSR1 (0.47) | NPSR1L3MBTL1CMA1PFKFB3PFKFB4 | |
| SCHEMBL5090711 | 0.71 | BCKDK (0.44) | KDM4EKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| EP-1597248-B1 | SULFONAMIDE DERIVATIVES AS PPAR MODULATORS | LILLY CO ELI (US) | 2007-12-26 | — | — | EP | disclosed |
| US-20060217433-A1 | Sulfonamide derivatives as ppar modulators | ELI LILLY AND COMPANY (US) | 2006-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060217433-A1 | Sulfonamide derivatives as ppar modulators | PPARD, PPARA, PPARG | NPSR1 466/4885L3MBTL1 4653/4885KDM4E 3238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.