Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.63 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ELANE | P08246 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3691267 | 0.92 | HPGD (0.58) | HPGDRAB9ANPC1ALDH1A1SRD5A2 | |
| SCHEMBL3690725 | 0.84 | L3MBTL1 (0.57) | HPGDRAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL1583011 | 0.82 | HPGD (0.54) | HPGDNPC1ALDH1A1SRD5A2MEN1 | |
| SCHEMBL607323 | 0.81 | MEN1 (0.63) | HPGDRAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL3798903 | 0.79 | ATM (0.50) | HPGDRAB9ANPC1ALDH1A1SRD5A2 | |
| SCHEMBL3691842 | 0.79 | HPGD (0.44) | HPGDRAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL3686294 | 0.78 | MAPT (0.48) | HPGDRAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL43585 | 0.78 | HPGD (1.00) | HPGDRAB9ANPC1ALDH1A1SRD5A2 | |
| Michler'S Ketone SCHEMBL3324670 | 0.78 | HPGD (1.00) | HPGDRAB9ANPC1ALDH1A1SRD5A2 | |
| SCHEMBL28230346 | 0.78 | HPGD (1.00) | HPGDRAB9ANPC1ALDH1A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231720-B1 | FUNCTIONALIZED POLYMER AND METHODS FOR MAKING AND USING | BRIDGESTONE CORP (JP) | 2013-08-14 | — | — | EP | disclosed |
| US-8236892-B2 | Functionalized polymer and methods for making and using | BRIDGESTONE CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20100311899-A1 | FUNCTIONALIZED POLYMER AND METHODS FOR MAKING AND USING | BRIDGESTONE CORPORATION (JP) | 2010-12-09 | — | — | US | disclosed |