Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3691267 | 0.84 | HPGD (0.58) | MAPTRAB9ANPC1HPGDKMT2A | |
| SCHEMBL1583011 | 0.83 | HPGD (0.54) | NPC1HPGDKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11897252 | 0.81 | CA12 (0.43) | MAPTRAB9AMAPK1NPC1KDM4E | |
| SCHEMBL610351 | 0.78 | MEN1 (0.35) | MAPTMAPK1HPGDKMT2AMEN1 | |
| SCHEMBL3687076 | 0.78 | HPGD (0.63) | MAPTRAB9ANPC1HPGDKMT2A | |
| SCHEMBL8191180 | 0.77 | MAPT (0.55) | MAPTRAB9AMAPK1NPC1KDM4E | |
| SCHEMBL1478754 | 0.76 | NOTUM (0.36) | MAPTRAB9AMAPK1NPC1KDM4E | |
| SCHEMBL3687994 | 0.76 | ALDH1A1 (0.43) | MAPTRAB9AMAPK1NPC1KDM4E | |
| SCHEMBL21630202 | 0.76 | MEN1 (0.50) | MAPTMAPK1HPGDKMT2AMEN1 | |
| SCHEMBL20003185 | 0.76 | MAPT (0.55) | MAPTRAB9AMAPK1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231720-B1 | FUNCTIONALIZED POLYMER AND METHODS FOR MAKING AND USING | BRIDGESTONE CORP (JP) | 2013-08-14 | — | — | EP | disclosed |
| US-8236892-B2 | Functionalized polymer and methods for making and using | BRIDGESTONE CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20100311899-A1 | FUNCTIONALIZED POLYMER AND METHODS FOR MAKING AND USING | BRIDGESTONE CORPORATION (JP) | 2010-12-09 | — | — | US | disclosed |