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Butylated Hydroxytoluene

Butylated Hydroxytoluene

SCHEMBL3687285

CC(C)(C)c1cccc(C(C)(C)C)c1O.CC(C)(C)c1cccc(C(C)(C)C)c1O.Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.78

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 4/20 0.78
▸ SMN1; SMN2 Q16637 4/20 0.78
▸ ALDH1A1 P00352 3/20 0.78
▸ POLB P06746 1/20 0.78
▸ TYR P14679 1/20 0.78
▸ GABRA1 P14867 1/20 0.63
▸ GABRB2 P47870 1/20 0.63
▸ HSPA5 P11021 1/20 0.57
▸ CYP2C9 P11712 3/20 0.55
▸ CYP2C19 P33261 3/20 0.55
▸ HIF1A Q16665 2/20 0.55
▸ CA1 P00915 2/20 0.54
▸ TSHR P16473 2/20 0.52
▸ TDP1 Q9NUW8 1/20 0.52
▸ PTGS1 P23219 2/20 0.52
▸ PTGS2 P35354 2/20 0.52
▸ CYP2D6 P10635 1/20 0.49
▸ HSD17B10 Q99714 1/20 0.49
▸ ALOX5 P09917 1/20 0.47
▸ ALOX12 P18054 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butylated Hydroxytoluene SCHEMBL9394538 1.00 CA2 (0.78) CA2SMN1; SMN2ALDH1A1POLBTYR
Butylated Hydroxytoluene SCHEMBL26905219 0.92 CA2 (0.67) CA2SMN1; SMN2ALDH1A1POLBTYR
SCHEMBL5611622 0.92 CA2 (0.67) CA2SMN1; SMN2ALDH1A1POLBTYR
Butylated Hydroxytoluene SCHEMBL6436436 0.89 SMN1; SMN2 (0.90) CA2SMN1; SMN2ALDH1A1POLBTYR
Butylated Hydroxytoluene SCHEMBL453824 0.89 SMN1; SMN2 (1.00) CA2SMN1; SMN2ALDH1A1POLBTYR
Butylated Hydroxytoluene SCHEMBL3950 0.89 SMN1; SMN2 (1.00) CA2SMN1; SMN2ALDH1A1POLBTYR
Butylated Hydroxytoluene SCHEMBL15789839 0.88 CA2 (0.72) CA2SMN1; SMN2ALDH1A1POLBTYR
SCHEMBL21905691 0.88 CA2 (0.68) CA2SMN1; SMN2ALDH1A1POLBTYR
Butylated Hydroxytoluene SCHEMBL7590469 0.88 ALDH1A1 (0.72) CA2SMN1; SMN2ALDH1A1POLBTYR
SCHEMBL22248521 0.88 CA2 (0.60) CA2SMN1; SMN2ALDH1A1POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2057256-B1 Method for improving the pour point of a lubricant composition EXXONMOBIL RES & ENG CO (US) 2018-05-09 — — EP disclosed
EP-2176389-B1 HYDROCARBON FLUIDS WITH IMPROVED POUR POINT EXXONMOBIL RES & ENG CO (US) 2015-12-23 — — EP disclosed
EP-2176389-A1 HYDROCARBON FLUIDS WITH IMPROVED POUR POINT ExxonMobil Research and Engineering Company (US) 2010-04-21 — — EP disclosed
EP-2057256-A2 LUBRICANT COMPOSITIONS HAVING IMPROVED LOW TEMPERATURE PROPERTIES ExxonMobil Research and Engineering Company (US) 2009-05-13 — — EP disclosed
EP-2038387-A1 LUBRICATING COMPOSITIONS ExxonMobil Research and Engineering Company (US) 2009-03-25 — — EP disclosed
WO-2009014752-A1 HYDROCARBON FLUIDS WITH IMPROVED POUR POINT EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2009-01-29 — — WO disclosed
EP-1975222-A1 Lubricant compositions with improved properties ExxonMobil Research and Engineering Company (US) 2008-10-01 — — EP disclosed
WO-2008115484-A1 LUBRICANT COMPOSITIONS WITH IMPROVED PROPERTIES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2008-09-25 — — WO disclosed
WO-2008016484-A2 LUBRICANT COMPOSITIONS HAVING IMPROVED LOW TEMPERATURE PROPERTIES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2008-02-07 — — WO disclosed
WO-2008002425-A1 LUBRICATING COMPOSITIONS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2008-01-03 — — WO disclosed