Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.68 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.60 |
| ▸ | TNKS | O95271 | 1/20 | 0.60 |
| ▸ | PARP1 | P09874 | 1/20 | 0.60 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.60 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NPY1R | P25929 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4659168 | 0.88 | MAOB (0.78) | MAOBALOX5CA1CA2CA9 | |
| SCHEMBL27430952 | 0.87 | MAOB (0.62) | MAOBP2RY14TNKSPARP1TNKS2 | |
| SCHEMBL11673327 | 0.85 | MAOB (0.58) | MAOBP2RY14TNKSPARP1TNKS2 | |
| SCHEMBL5768216 | 0.84 | MAOB (0.72) | MAOBTNKSPARP1TNKS2ALOX5 | |
| SCHEMBL31105656 | 0.84 | MAOB (0.71) | MAOBTNKSPARP1TNKS2ALOX5 | |
| SCHEMBL731363 | 0.84 | MAOB (0.71) | MAOBTNKSPARP1TNKS2ALOX5 | |
| SCHEMBL733971 | 0.82 | MAOB (0.61) | MAOBTNKSPARP1TNKS2PARP2 | |
| SCHEMBL11850978 | 0.82 | MAOB (0.80) | MAOBTNKSPARP1TNKS2PARP2 | |
| SCHEMBL11699010 | 0.82 | MAOB (0.78) | MAOBTNKSPARP1TNKS2PARP2 | |
| SCHEMBL17427775 | 0.82 | MAOB (0.62) | MAOBTNKSPARP1TNKS2PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110386909-B | Method for synthesizing benzofuran derivative through copper-free ligand-free palladium catalyst | 中国科学院青岛生物能源与过程研究所 | 2023-07-07 | — | — | CN | disclosed |
| CN-109574965-B | Preparation and application of 2- (4-substituent phenyl) -3-formamide benzofuran alkene cyanide compound | 上海交通大学 | 2022-12-30 | — | — | CN | disclosed |
| US-20210384446-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2021-12-09 | — | — | US | disclosed |
| US-11133478-B2 | Aromatic amine derivative and organic electroluminescent device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2021-09-28 | — | — | US | disclosed |
| US-11033889-B2 | Palladium acyclic diaminocarbene complexes as precatalysts for Hiyama coupling and the tandem one-pot fluoride free Hiyama coupling/cyclization for the synthesis of biologically relevant | INDIAN INSTITUTE OF TECHNOLOGY BOMBAY (IN) | 2021-06-15 | — | — | US | disclosed |
| US-11033889-B2 | Palladium acyclic diaminocarbene complexes as precatalysts for Hiyama coupling and the tandem one-pot fluoride free Hiyama coupling/cyclization for the synthesis of biologically relevant | INDIAN INSTITUTE OF TECHNOLOGY BOMBAY (IN) | 2021-06-15 | — | — | US | disclosed |
| US-20210057649-A1 | PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING DEVICE | SONY CORPORATION (JP) | 2021-02-25 | — | — | US | disclosed |
| US-20200122132-A1 | PALLADIUM ACYCLIC DIAMINOCARBENE COMPLEXES AS PRECATALYSTS FOR HIYAMA COUPLING AND THE TANDEM ONE-POT FLUORIDE FREE HIYAMA COUPLING/CYCLIZATION FOR THE SYNTHESIS OF BIOLOGICALLY RELEVANT | INDIAN INSTITUTE OF TECHNOLOGY BOMBAY (IN) | 2020-04-23 | — | — | US | disclosed |
| US-20200122132-A1 | PALLADIUM ACYCLIC DIAMINOCARBENE COMPLEXES AS PRECATALYSTS FOR HIYAMA COUPLING AND THE TANDEM ONE-POT FLUORIDE FREE HIYAMA COUPLING/CYCLIZATION FOR THE SYNTHESIS OF BIOLOGICALLY RELEVANT | INDIAN INSTITUTE OF TECHNOLOGY BOMBAY (IN) | 2020-04-23 | — | — | US | disclosed |
| CN-110386909-A | A method of benzofuran derivatives are synthesized by no copper catalysis of ligand-free palladium agent | 中国科学院青岛生物能源与过程研究所 | 2019-10-29 | — | — | CN | disclosed |
| US-4117128-A | SULFONYL BENZOFURANS AND BENZOTHIOPHENES HAVING CORONARY VASODILATOR ACTIVITY | SMITHKLINE CORPORATION (US) | 1978-09-26 | — | — | US | disclosed |
| US-4024273-A | Coronary vasodilator and anti-anginal compositions comprising substituted benzofurans and benzothiophenes and methods of producing coronary vasodilation and anti-anginal activity | SMITHKLINE CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-4022772-A | OPTICAL BRIGHTENING | CIBA-GEIGY CORPORATION (US) | 1977-05-10 | — | — | US | disclosed |
| US-4013642-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |
| US-3993645-A | Stilbene optical brighteners and compositions brightened therewith | STERLING DRUG INC. (US) | 1976-11-23 | — | — | US | disclosed |
| US-3983245-A | CORONARY VASODILATORS | SMITHKLINE CORPORATION (US) | 1976-09-28 | — | — | US | disclosed |
| US-3975537-A | SUBSTITUTED BENZOFURANS | SMITH KLINE (US) | 1976-08-17 | — | — | US | disclosed |
| US-3974144-A | BENZOFURAN, BENZOTHIOPHENE, NAPHTHOFURAN, OPTICAL BRIGHTENER | STERLING DRUG INC. (US) | 1976-08-10 | — | — | US | disclosed |
| US-3947470-A | CORONARY VASODILATORS, TREATMENT OF ANGINA PECTORIS | SMITHKLINE CORPORATION (US) | 1976-03-30 | — | — | US | disclosed |
| US-3932301-A | NYLON, POLYESTERS | STERLING DRUG INC. (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200122132-A1 | PALLADIUM ACYCLIC DIAMINOCARBENE COMPLEXES AS PRECATALYSTS FOR HIYAMA COUPLING AND THE TANDEM ONE-POT FLUORIDE FREE HIYAMA COUPLING/CYCLIZATION FOR THE SYNTHESIS OF BIOLOGICALLY RELEVANT | PAICS, AOC1, FLI1 | MAOB 351/4885P2RY14 4167/4885TNKS 2224/4885 |
| US-20210384446-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | DDT, TYR, DDC | MAOB 39/4885P2RY14 1904/4885TNKS 3491/4885 |
| US-11133478-B2 | Aromatic amine derivative and organic electroluminescent device using the same | DDT, TYR, DDC | MAOB 39/4885P2RY14 1904/4885TNKS 3491/4885 |
| US-11033889-B2 | Palladium acyclic diaminocarbene complexes as precatalysts for Hiyama coupling and the tandem one-pot fluoride free Hiyama coupling/cyclization for the synthesis of biologically relevant | PAICS, AOC1, FLI1 | MAOB 351/4885P2RY14 4167/4885TNKS 2224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.