SCHEMBL3687633

SCHEMBL3687633

CO[Si](CCCN(C1CCCCC1)C1CCCCC1)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.33
KMT2A Q03164 6/20 0.33
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
GAA P10253 2/20 0.33
LMNA P02545 2/20 0.31
THRA P10827 1/20 0.31
THRB P10828 1/20 0.31
ADH1A P07327 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15360603 0.80 ADH1A (0.31) LMNAADH1A
SCHEMBL15361126 0.77
SCHEMBL12802045 0.76 LMNA (0.32) GAALMNA
SCHEMBL15360764 0.76
SCHEMBL15360883 0.75 ADH1A (0.30) ADH1A
SCHEMBL10170018 0.75 SIGMAR1 (0.38) MEN1KMT2AALDH1A1SMN1; SMN2GAA
SCHEMBL22574003 0.73 EPHX1 (0.38) MEN1KMT2AALDH1A1SMN1; SMN2GAA
SCHEMBL15360645 0.73
SCHEMBL615094 0.73
SCHEMBL10171077 0.73 SIGMAR1 (0.41) MEN1KMT2AALDH1A1SMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2591856-A1 Plant with catalyst for dismutation of halogen silanes containing hydrogen Evonik Degussa GmbH (DE) 2013-05-15 EP disclosed
US-20100296994-A1 CATALYST AND METHOD FOR DISMUTATION OF HALOSILANES CONTAINING HYDROGEN EVONIK DEGUSSA GMBH (DE) 2010-11-25 US disclosed
US-4950701-A POLYSILOXANE ADHESIVE WITH A AROMATIC AMINE PROMOTER CEMEDINE COMPANY, LTD. (JP) 1990-08-21 US disclosed
US-4793886-A TWO PART-CYANOACRYLATE AND 1,1-DISUBSTITUTED COMPOUND WITH SELF-CURING ADHESIVE CEMEDINE CO., LTD. (JP) 1988-12-27 US disclosed