Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.64 |
| ▸ | CA12 | O43570 | 3/20 | 0.64 |
| ▸ | CA1 | P00915 | 3/20 | 0.64 |
| ▸ | CA7 | P43166 | 3/20 | 0.64 |
| ▸ | CA9 | Q16790 | 3/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.64 |
| ▸ | CA3 | P07451 | 1/20 | 0.64 |
| ▸ | TYR | P14679 | 1/20 | 0.64 |
| ▸ | DRD1 | P21728 | 1/20 | 0.64 |
| ▸ | CA4 | P22748 | 1/20 | 0.64 |
| ▸ | CA6 | P23280 | 1/20 | 0.64 |
| ▸ | CA5A | P35218 | 1/20 | 0.64 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.64 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL28778321 | 0.92 | TSHR (0.57) | CA2CA12CA1CA7CA9 | |
| Paraben SCHEMBL27174174 | 0.87 | CA2 (0.76) | CA2CA12CA1CA7CA9 | |
| Paraben SCHEMBL3692910 | 0.84 | CA2 (0.64) | CA2CA12CA1CA7CA9 | |
| Paraben SCHEMBL3695383 | 0.84 | CA2 (0.64) | CA2CA12CA1CA7CA9 | |
| Benzoic Acid SCHEMBL1833217 | 0.83 | TSHR (0.61) | SRD5A2TP53TSHRKMT2AALDH1A1 | |
| Paraben SCHEMBL3695523 | 0.83 | CA2 (0.70) | CA2CA12CA1CA7CA9 | |
| Aminobenzoic Acid SCHEMBL5875021 | 0.82 | TP53 (0.46) | CA2CA12CA1CA7CA9 | |
| Paraben SCHEMBL2648402 | 0.81 | CA2 (0.80) | CA2CA12CA1CA7CA9 | |
| Paraben SCHEMBL27392236 | 0.80 | CA2 (0.89) | CA2CA12CA1CA7CA9 | |
| Paraben SCHEMBL1685428 | 0.80 | CA2 (0.89) | CA2CA12CA1CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292329-A1 | 4-HYDROXY BENZOATE DERIVATIVES FOR USE IN THE TREATMENT OF INFECTION, INFLAMMATION OR PAIN | JORDAN ROY ARLINGTON | 2010-11-18 | — | — | US | claimed |
| WO-2008155520-A2 | 4-HYDROXY BENZOATE DERIVATIVES FOR USE IN THE TREATMENT OF INFECTION, INFLAMMATION OR PAIN | JORDAN ROY ARLINGTON (GB) | 2008-12-24 | — | — | WO | claimed |
| US-9090555-B2 | 4-hydroxy benzoate derivatives for use in the treatment of infection, inflammation or pain | JORDAN ROY ARLINGTON (GB) | 2015-07-28 | — | — | US | disclosed |
| US-20150005383-A1 | 4-HYDROXY BENZOATE DERIVATIVES FOR USE IN THE TREATMENT OF INFECTION, INFLAMMATION OR PAIN | JORDAN ROY ARLINGTON (GB) | 2015-01-01 | — | — | US | disclosed |
| US-8785504-B2 | 4-hydroxy benzoate derivatives for use in the treatment of infection, inflammation or pain | JORDAN ROY ARLINGTON (GB) | 2014-07-22 | — | — | US | disclosed |
| US-20100292329-A1 | 4-HYDROXY BENZOATE DERIVATIVES FOR USE IN THE TREATMENT OF INFECTION, INFLAMMATION OR PAIN | JORDAN ROY ARLINGTON | 2010-11-18 | — | — | US | disclosed |
| WO-2008155520-A2 | 4-HYDROXY BENZOATE DERIVATIVES FOR USE IN THE TREATMENT OF INFECTION, INFLAMMATION OR PAIN | JORDAN ROY ARLINGTON (GB) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005383-A1 | 4-HYDROXY BENZOATE DERIVATIVES FOR USE IN THE TREATMENT OF INFECTION, INFLAMMATION OR PAIN | HRH1, HRH2, FPR1 | CA2 1165/4885CA12 3087/4885CA1 2911/4885 |
| US-20100292329-A1 | 4-HYDROXY BENZOATE DERIVATIVES FOR USE IN THE TREATMENT OF INFECTION, INFLAMMATION OR PAIN | HRH1, HRH2, FPR1 | CA2 1165/4885CA12 3087/4885CA1 2911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.