Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.35 |
| ▸ | PI4KA | P42356 | 5/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472326 | 0.80 | SMN1; SMN2 (0.38) | AXLGFERALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL360736 | 0.77 | HTT (0.41) | AXLGFERALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL19329221 | 0.77 | ALDH1A1 (0.38) | AXLGFERALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL359702 | 0.77 | SMN1; SMN2 (0.36) | AXLGFERALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL368876 | 0.77 | KMT2A (0.33) | — | |
| SCHEMBL31456648 | 0.73 | CYP3A4 (0.37) | AXLGFERALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL19783056 | 0.69 | GAA (0.42) | AXLGFERALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL30858956 | 0.68 | EGFR (0.37) | AXLGFERALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL9072335 | 0.68 | EGFR (0.37) | AXLGFERALDH1A1SMN1; SMN2TP53 | |
| Bromide SCHEMBL28941201 | 0.68 | GAA (0.41) | AXLGFERALDH1A1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007510-A1 | COMPOUNDS FOR BINDING AND IMAGING AMYLOID PLAQUES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | disclosed |