Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 2/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3693379 | 1.00 | MAPT (0.44) | MAPTMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL3689343 | 0.91 | P4HB (0.43) | MAPTSNCATERTBCHEACHE | |
| SCHEMBL3691580 | 0.85 | BCHE (0.56) | MAPTMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL3696162 | 0.85 | BCHE (0.56) | MAPTMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL5915556 | 0.84 | MAPT (0.44) | MAPTMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL5915721 | 0.84 | MAPT (0.44) | MAPTMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL3692346 | 0.84 | BCHE (0.57) | BCHE | |
| SCHEMBL3682839 | 0.84 | BCHE (0.57) | BCHE | |
| SCHEMBL3687869 | 0.83 | BCHE (0.54) | MAPTMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL3686241 | 0.82 | PTPN1 (0.45) | MAPTMEN1ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642367-B2 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2010-01-05 | — | — | US | disclosed |
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | disclosed |