Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 2/20 | 0.43 |
| ▸ | SNCA | P37840 | 2/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3693379 | 0.91 | MAPT (0.44) | SNCATERTMAPTBCHEACHE | |
| SCHEMBL3689339 | 0.91 | MAPT (0.44) | SNCATERTMAPTBCHEACHE | |
| SCHEMBL3691582 | 0.85 | BCHE (0.56) | P4HBMAPTBCHEACHE | |
| SCHEMBL30384875 | 0.85 | BCHE (0.56) | P4HBMAPTBCHEACHE | |
| SCHEMBL25184970 | 0.85 | BCHE (0.56) | P4HBMAPTBCHEACHE | |
| SCHEMBL5915562 | 0.84 | P4HB (0.46) | P4HBSNCATERTMAPTBCHE | |
| SCHEMBL3682843 | 0.84 | P4HB (0.57) | P4HBBCHE | |
| SCHEMBL3687867 | 0.83 | BCHE (0.54) | MAPTBCHEACHE | |
| SCHEMBL3690207 | 0.83 | BCHE (0.54) | MAPTBCHEACHE | |
| SCHEMBL3685872 | 0.82 | MAOB (0.42) | MAPTBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | claimed |
| EP-1506158-A2 | DIAMINO-FUNCTIONAL CHALCONES | Lica Pharmaceuticals A/S (DK) | 2005-02-16 | — | — | EP | claimed |
| WO-2003097576-A2 | DIAMINO-FUNCTIONAL CHALCONES | LICA PHARMACEUTICALS A/S (DK) | 2003-11-27 | — | — | WO | claimed |
| US-7642367-B2 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2010-01-05 | — | — | US | disclosed |
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | disclosed |