Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | JUND | P17535 | 1/20 | 0.39 |
| ▸ | FOSB | P53539 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218091 | 0.82 | HTR1A (0.45) | HTR1AADRA1DADRA1AADRA1BCYP1A2 | |
| SCHEMBL3689420 | 0.77 | KCNH2 (0.52) | KDM4EGAAHTTKCNH2ALDH1A1 | |
| SCHEMBL3692137 | 0.75 | MEN1 (0.49) | MEN1KMT2A | |
| SCHEMBL8821601 | 0.74 | KDM1A (0.56) | MEN1KMT2AKDM4EGAAHTT | |
| SCHEMBL8821304 | 0.74 | TACR1 (0.50) | TACR1 | |
| SCHEMBL8696023 | 0.74 | MEN1 (0.60) | MEN1KMT2AGAATACR1ALDH1A1 | |
| SCHEMBL29862532 | 0.72 | HTR1A (0.55) | HTR1AADRA1DADRA1AADRA1BCYP1A2 | |
| SCHEMBL24716111 | 0.72 | HTR2C (0.56) | HTR1AADRA1DADRA1AADRA1BJUND | |
| SCHEMBL30626631 | 0.72 | HTR2C (0.56) | HTR1AADRA1DADRA1AADRA1BJUND | |
| Hydrochloric Acid SCHEMBL23360306 | 0.71 | HTR1A (0.54) | HTR1AADRA1DADRA1AADRA1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2239260-A1 | Novel compounds with antibacterial activity | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2010-10-13 | — | — | EP | disclosed |
| EP-1551829-A2 | NOVEL COMPOUNDS WITH ANTIBACTERIAL ACTIVITY | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004035569-A2 | NOVEL COMPOUNDS WITH ANTIBACTERIAL ACTIVITY | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2004-04-29 | — | — | WO | disclosed |