Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ESRRA | P11474 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1532883 | 0.88 | ELANE (0.44) | MAPTS1PR4PDK2CA12CA1 | |
| SCHEMBL141537 | 0.87 | PGR (0.49) | PGRMAPTENPP3PARP10PARP11 | |
| SCHEMBL31026066 | 0.87 | PGR (0.49) | PGRMAPTENPP3PARP10PARP11 | |
| SCHEMBL17183131 | 0.84 | ELANE (0.44) | MAPTS1PR4ENPP3PDK2CA12 | |
| SCHEMBL7776584 | 0.84 | ESR2 (0.53) | PGRMAPTENPP3PARP10PARP11 | |
| SCHEMBL278217 | 0.83 | S1PR4 (0.53) | MAPTS1PR4FYNCLK4DYRK1B | |
| SCHEMBL10341375 | 0.82 | ESR2 (0.55) | PGRMAPTENPP3PARP10PARP11 | |
| SCHEMBL139182 | 0.81 | ESRRA (0.46) | S1PR4ESRRA | |
| SCHEMBL30445989 | 0.81 | ESRRA (0.46) | S1PR4ESRRA | |
| SCHEMBL6300449 | 0.79 | ESR2 (0.44) | PGRMAPTENPP3PARP10PARP11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010016858-A2 | MOLECULAR IMAGING PROBES | CARESTREAM HEALTH, INC. (US) | 2010-02-11 | — | — | WO | disclosed |