SCHEMBL7776584

SCHEMBL7776584

Cc1cccc(-c2ccc(-c3ccc(-c4ccccc4)cc3C)cc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.53
PGR P06401 1/20 0.47
MAPT P10636 2/20 0.47
PDK2 Q15119 1/20 0.45
NPC1 O15118 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ENPP3 O14638 2/20 0.44
CNR2 P34972 2/20 0.44
CNR1 P21554 1/20 0.44
PARP10 Q53GL7 1/20 0.43
PARP11 Q9NR21 1/20 0.43
POLB P06746 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
PDE3B Q13370 1/20 0.42
PDE3A Q14432 1/20 0.42
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10341375 0.98 ESR2 (0.55) ESR2PGRMAPTPDK2NPC1
SCHEMBL5013854 0.90 ESR2 (0.63) ESR2MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL16192737 0.90 ESR2 (0.63) ESR2MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL31026066 0.88 PGR (0.49) ESR2PGRMAPTPDK2NPC1
SCHEMBL141537 0.88 PGR (0.49) ESR2PGRMAPTPDK2NPC1
SCHEMBL6300449 0.87 ESR2 (0.44) ESR2PGRMAPTPDK2NPC1
SCHEMBL9717669 0.86 TSHR (0.47) ESR2PGRMAPTPDK2NPC1
SCHEMBL20689786 0.85 TSHR (0.55) PGRMAPTPDK2NPC1HPGD
SCHEMBL20986881 0.85 ENPP3 (0.46) ESR2PGRMAPTPDK2NPC1
SCHEMBL3689436 0.84 PGR (0.44) ESR2PGRMAPTPDK2ENPP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1126319-A1 PHOTOSENSITIVE RESIN COMPOSITION AND METHOD OF IMPROVING DRY ETCHING RESISTANCE OF PHOTOSENSITIVE RESIN COMPOSITION CLARIANT INTERNATIONAL LTD. (CH) 2001-08-22 EP disclosed