SCHEMBL523395

SCHEMBL523395

O=C(O)n1nc2ccccc2n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 6/20 0.44
MAPT P10636 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MGAM O43451 3/20 0.39
ALOX15 P16050 2/20 0.38
HSD17B10 Q99714 1/20 0.38
F2 P00734 1/20 0.37
AMY1A P0DUB6 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
SLC9A1 P19634 1/20 0.37
KMT2A Q03164 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
PARP1 P09874 1/20 0.37
TSHR P16473 2/20 0.36
DAO P14920 1/20 0.36
NAPRT Q6XQN6 1/20 0.36
CES2 O00748 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8156271 0.79 HPGD (0.50) HPGDKDM4EALDH1A1MAPTSMN1; SMN2
SCHEMBL11883102 0.78 PARP1 (0.40) HPGDKDM4EALDH1A1MAPTSMN1; SMN2
SCHEMBL8143932 0.78 NPC1 (0.44) HPGDKDM4EALDH1A1MAPTSMN1; SMN2
SCHEMBL31707307 0.78 HPGD (0.40) HPGDKDM4EALDH1A1MAPTSMN1; SMN2
SCHEMBL11294552 0.74 SMN1; SMN2 (0.48) KDM4EALDH1A1MAPTSMN1; SMN2ALOX15
SCHEMBL11751025 0.73 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2KMT2A
SCHEMBL27649968 0.73 L3MBTL1 (0.46) HPGDKDM4EALDH1A1MAPTSMN1; SMN2
SCHEMBL3689757 0.73 KDM4E (0.40) HPGDKDM4EALDH1A1MAPTSMN1; SMN2
SCHEMBL20818702 0.72 DGAT1 (0.43) HPGDKDM4EALDH1A1MAPTSMN1; SMN2
SCHEMBL19733536 0.71 KDM4E (0.43) HPGDKDM4EALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118599238-B PVC plastic particle applied to outdoor furniture and preparation method thereof 广东领航新材料有限公司 2025-03-07 CN claimed
CN-118599238-A PVC plastic particle applied to outdoor furniture and preparation method thereof 广东领航新材料有限公司 2024-09-06 CN claimed
US-8735161-B2 Gas sensor incorporating a porous framework THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-05-27 US claimed
US-20130295680-A1 GAS SENSOR INCORPORATING A POROUS FRAMEWORK BASF SE 2013-11-07 US claimed
US-8480955-B2 Gas sensor incorporating a porous framework THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-07-09 US claimed
US-8480792-B2 Preparation of functionalized zeolitic frameworks THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-07-09 US claimed
US-20120028846-A1 GAS SENSOR INCORPORATING A POROUS FRAMEWORK BASF SE (DE) 2012-02-02 US claimed
EP-2356072-A1 A GAS SENSOR INCORPORATING A POROUS FRAMEWORK The Regents of the University of California (US) 2011-08-17 EP claimed
US-20100186588-A1 PREPARATION OF FUNCTIONALIZED ZEOLITIC FRAMEWORKS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-07-29 US claimed
WO-2010078337-A1 A GAS SENSOR INCORPORATING A POROUS FRAMEWORK THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-07-08 WO claimed
US-20100132549-A1 ADSORPTIVE GAS SEPARATION OF MULTI-COMPONENT GASES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-06-03 US claimed
EP-2167511-A2 PREPARATION OF FUNCTIONALIZED ZEOLITIC FRAMEWORKS The Regents of the University of California (US) 2010-03-31 EP claimed
EP-2155608-A1 ADSORPTIVE GAS SEPARATION OF MULTI-COMPONENT GASES The Regents Of The University Of California (US) 2010-02-24 EP claimed
WO-2009020745-A9 PREPARATION OF FUNCTIONALIZED ZEOLITIC FRAMEWORKS UNIV CALIFORNIA (US) 2009-07-02 WO claimed
WO-2009020745-A2 PREPARATION OF FUNCTIONALIZED ZEOLITIC FRAMEWORKS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-02-12 WO claimed
WO-2008140788-A1 ADSORPTIVE GAS SEPARATION OF MULTI-COMPONENT GASES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-11-20 WO claimed
EP-1988996-A2 PREPARATION OF FUNCTIONALIZED ZEOLITIC FRAMEWORKS The Regents of the University of Michigan (US) 2008-11-12 EP claimed
WO-2007101241-A2 PREPARATION OF FUNCTIONALIZED ZEOLITIC FRAMEWORKS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2007-09-07 WO claimed
US-20070202038-A1 PREPARATION OF FUNCTIONALIZED ZEOLITIC FRAMEWORKS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2007-08-30 US claimed
CN-120044756-A Photosensitive resin composition 旭化成株式会社 2025-05-27 CN disclosed
CN-118599238-B PVC plastic particle applied to outdoor furniture and preparation method thereof 广东领航新材料有限公司 2025-03-07 CN disclosed
CN-118599238-A PVC plastic particle applied to outdoor furniture and preparation method thereof 广东领航新材料有限公司 2024-09-06 CN disclosed
CN-118272809-A Release film and method for producing same 南亚塑胶工业股份有限公司 2024-07-02 CN disclosed
US-20230143425-A1 IMPROVEMENTS RELATED TO SORBENT MEDIA GENESIS SYSTEMS LLC 2023-05-11 US disclosed
US-20230024571-A1 CARBON DIOXIDE AND HUMIDITY CAPTURE SYSTEM AND METHOD GENESIS SYSTEMS LLC 2023-01-26 US disclosed
EP-4103304-A1 CARBON DIOXIDE AND HUMIDITY CAPTURE SYSTEM AND METHOD Molecule RND Limited (IE) 2022-12-21 EP disclosed
EP-4090455-A1 IMPROVEMENTS RELATED TO SORBENT MEDIA Molecule RND Limited (IE) 2022-11-23 EP disclosed
EP-2358726-B1 POROUS REACTIVE FRAMEWORKS UNIV CALIFORNIA (US) 2017-08-02 EP disclosed
US-9512145-B2 Porous reactive framework THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-12-06 US disclosed
US-8809546-B2 Preparation of functionalized zeolitic frameworks THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-08-19 US disclosed
US-8735161-B2 Gas sensor incorporating a porous framework THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-05-27 US disclosed
US-20130295680-A1 GAS SENSOR INCORPORATING A POROUS FRAMEWORK BASF SE 2013-11-07 US disclosed
US-8540802-B2 Adsorptive gas separation of multi-component gases THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-09-24 US disclosed
US-8480955-B2 Gas sensor incorporating a porous framework THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-07-09 US disclosed
US-8480792-B2 Preparation of functionalized zeolitic frameworks THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-07-09 US disclosed
US-20130023402-A1 Preparation of Functionalized Zeolitic Frameworks THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2013-01-24 US disclosed
US-8314245-B2 Preparation of functionalized zeolitic frameworks THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2012-11-20 US disclosed
CN-101389723-B Iodate-containing chemical-mechanical polishing composition and method CABOT MICROELECTRONICS CORP 2012-05-30 CN disclosed
US-20120028846-A1 GAS SENSOR INCORPORATING A POROUS FRAMEWORK BASF SE (DE) 2012-02-02 US disclosed
US-20110319630-A1 POROUS REACTIVE FRAMEWORK BASF SE (DE) 2011-12-29 US disclosed
US-8048537-B2 Cyclometalated transition metal complex and organic light emitting device using the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-11-01 US disclosed
EP-2358726-A2 POROUS REACTIVE FRAMEWORKS The Regents of the University of California (US) 2011-08-24 EP disclosed
EP-2356072-A1 A GAS SENSOR INCORPORATING A POROUS FRAMEWORK The Regents of the University of California (US) 2011-08-17 EP disclosed
US-20100186588-A1 PREPARATION OF FUNCTIONALIZED ZEOLITIC FRAMEWORKS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-07-29 US disclosed
WO-2010080618-A2 POROUS REACTIVE FRAMEWORKS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-07-15 WO disclosed
WO-2010078337-A1 A GAS SENSOR INCORPORATING A POROUS FRAMEWORK THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-07-08 WO disclosed
US-20100132549-A1 ADSORPTIVE GAS SEPARATION OF MULTI-COMPONENT GASES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-06-03 US disclosed
EP-2167511-A2 PREPARATION OF FUNCTIONALIZED ZEOLITIC FRAMEWORKS The Regents of the University of California (US) 2010-03-31 EP disclosed
EP-2155608-A1 ADSORPTIVE GAS SEPARATION OF MULTI-COMPONENT GASES The Regents Of The University Of California (US) 2010-02-24 EP disclosed
WO-2009020745-A9 PREPARATION OF FUNCTIONALIZED ZEOLITIC FRAMEWORKS UNIV CALIFORNIA (US) 2009-07-02 WO disclosed
CN-101432070-A Preparation of functionalized zeolite frameworks UNIV MICHIGAN (US) 2009-05-13 CN disclosed
CN-101389723-A Iodate-containing chemical-mechanical polishing composition and method CABOT MICROELECTRONICS CORP (US) 2009-03-18 CN disclosed
WO-2009020745-A2 PREPARATION OF FUNCTIONALIZED ZEOLITIC FRAMEWORKS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-02-12 WO disclosed
WO-2008140788-A1 ADSORPTIVE GAS SEPARATION OF MULTI-COMPONENT GASES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-11-20 WO disclosed
EP-1988996-A2 PREPARATION OF FUNCTIONALIZED ZEOLITIC FRAMEWORKS The Regents of the University of Michigan (US) 2008-11-12 EP disclosed
CN-101305005-A Novel diazaspiroalkanes and their use for treatment of CCR8 mediated diseases ASTRAZENECA AB (SE) 2008-11-12 CN disclosed
WO-2007101241-A2 PREPARATION OF FUNCTIONALIZED ZEOLITIC FRAMEWORKS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2007-09-07 WO disclosed
US-20070202038-A1 PREPARATION OF FUNCTIONALIZED ZEOLITIC FRAMEWORKS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2007-08-30 US disclosed
US-20070184303-A1 Cyclometalated transition metal complex and organic light emitting device using the same SAMSUNG DISPLAY CO., LTD. (KR) 2007-08-09 US disclosed
CN-1189467-C Pharmaceutically active sulfonamide derivatives APPLIED RES SYSTEM ARS HOLDING (AN) 2005-02-16 CN disclosed
CN-1377347-A Pharmaceutically active sulfonamide derivatives APPLIED RESEARCH SYSTEMS (NL) 2002-10-30 CN disclosed
CN-1377347-A Pharmaceutically active sulfonamide derivatives APPLIED RESEARCH SYSTEMS (NL) 2002-10-30 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130023402-A1 Preparation of Functionalized Zeolitic Frameworks SOD1, HNRNPF, GTF2F1 HPGD 3253/4885KDM4E 1297/4885ALDH1A1 4095/4885
US-20070202038-A1 PREPARATION OF FUNCTIONALIZED ZEOLITIC FRAMEWORKS SOD1, HNRNPF, GTF2F1 HPGD 3253/4885KDM4E 1297/4885ALDH1A1 4095/4885
US-20110319630-A1 POROUS REACTIVE FRAMEWORK OGFR, EPCAM, PTGFR HPGD 1784/4885KDM4E 3253/4885ALDH1A1 1723/4885
US-20100186588-A1 PREPARATION OF FUNCTIONALIZED ZEOLITIC FRAMEWORKS SOD1, HNRNPF, GTF2F1 HPGD 3253/4885KDM4E 1297/4885ALDH1A1 4095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.