Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | EYA2 | O00167 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263592 | 0.95 | AKR1B1 (0.50) | AKR1B1MEN1KMT2ARECQLHTR1A | |
| SCHEMBL8966423 | 0.93 | AKR1B1 (0.55) | AKR1B1MEN1KMT2ARECQLHTR1A | |
| SCHEMBL29393657 | 0.93 | AKR1B1 (0.55) | AKR1B1MEN1KMT2ARECQLHTR1A | |
| SCHEMBL453848 | 0.93 | AKR1B1 (0.55) | AKR1B1MEN1KMT2ARECQLHTR1A | |
| SCHEMBL23629774 | 0.92 | AKR1B1 (0.53) | AKR1B1MEN1KMT2ARECQLHTR1A | |
| Water SCHEMBL505782 | 0.92 | AKR1B1 (0.53) | AKR1B1MEN1KMT2ARECQLHTR1A | |
| SCHEMBL8939988 | 0.92 | AKR1B1 (0.53) | AKR1B1MEN1KMT2ARECQLHTR1A | |
| SCHEMBL15864891 | 0.92 | AKR1B1 (0.53) | AKR1B1MEN1KMT2ARECQLHTR1A | |
| SCHEMBL1314141 | 0.92 | AKR1B1 (0.53) | AKR1B1MEN1KMT2ARECQLHTR1A | |
| Hydrochloric Acid SCHEMBL935435 | 0.92 | AKR1B1 (0.53) | AKR1B1MEN1KMT2ARECQLHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9968633-B2 | Stimuli responsive compositions for iron chelation | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2018-05-15 | — | — | US | claimed |
| US-20170239182-A1 | PHARMACEUTICAL FORMULATIONS OF AND METHODS TO PREPARE CHELATING AGENTS FOR EFFICIENT METAL REMOVAL TREATMENT SYSTEMS | HAYES MARK E (US) | 2017-08-24 | — | — | US | claimed |
| US-20170231910-A1 | PHARMACEUTICAL FORMULATIONS OF CHELATING AGENTS AS A METAL REMOVAL TREATMENT SYSTEM | HAYES MARK E (US) | 2017-08-17 | — | — | US | claimed |
| US-20160184344-A1 | STIMULI RESPONSIVE COMPOSITIONS FOR IRON CHELATION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-06-30 | — | — | US | claimed |
| WO-2016025559-A1 | PHARMACEUTICAL FORMULATIONS OF AND METHODS TO PREPARE CHELATING AGENTS FOR EFFICIENT METAL REMOVAL TREATMENT SYSTEMS | ZONEONE PHARMA, INC. (US) | 2016-02-18 | — | — | WO | claimed |
| WO-2016025611-A2 | PHARMACEUTICAL FORMULATIONS OF CHELATING AGENTS AS A METAL REMOVAL TREATMENT SYSTEM | ZONEONE PHARMA, INC. (US) | 2016-02-18 | — | — | WO | claimed |
| WO-2014153192-A1 | PHARMACEUTICAL FORMULATIONS OF CHELATING AGENTS AS A METAL REMOVAL TREATMENT SYSTEM | ZONEONE PHARMA, INC. (US) | 2014-09-25 | — | — | WO | claimed |
| US-20140271825-A1 | PHARMACEUTICAL FORMULATIONS OF CHELATING AGENTS AS A METAL REMOVAL TREATMENT SYSTEM | ZONEONE PHARMA, INC. | 2014-09-18 | — | — | US | claimed |
| EP-0225051-B1 | THE TREATMENT OF AQUEOUS SYSTEMS | W.R. Grace & Co.-Conn. (US) | 1992-02-19 | — | — | EP | claimed |
| US-4778655-A | CORROSION INHIBITION BY ADDING SOLUBLE ZINC SALT, CHELATING AGENT, COMPOUND HAVING BOTH A PHOSPHOROUS AND A CARBOXYL GROUP | W. R. GRACE & CO. (US) | 1988-10-18 | — | — | US | claimed |
| EP-0225051-A1 | The treatment of aqueous systems | W.R. Grace & Co.-Conn. (US) | 1987-06-10 | — | — | EP | claimed |
| US-9968633-B2 | Stimuli responsive compositions for iron chelation | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2018-05-15 | — | — | US | disclosed |
| US-20170239182-A1 | PHARMACEUTICAL FORMULATIONS OF AND METHODS TO PREPARE CHELATING AGENTS FOR EFFICIENT METAL REMOVAL TREATMENT SYSTEMS | HAYES MARK E (US) | 2017-08-24 | — | — | US | disclosed |
| US-20170231910-A1 | PHARMACEUTICAL FORMULATIONS OF CHELATING AGENTS AS A METAL REMOVAL TREATMENT SYSTEM | HAYES MARK E (US) | 2017-08-17 | — | — | US | disclosed |
| US-20170209400-A1 | METHODS AND TOPICAL FORMULATIONS FOR TREATING INFLAMMATION | LIVIONEX INC (US) | 2017-07-27 | — | — | US | disclosed |
| US-4778655-A | CORROSION INHIBITION BY ADDING SOLUBLE ZINC SALT, CHELATING AGENT, COMPOUND HAVING BOTH A PHOSPHOROUS AND A CARBOXYL GROUP | W. R. GRACE & CO. (US) | 1988-10-18 | — | — | US | disclosed |
| US-4338460-A | Process for preparing chelating agents | W. R. GRACE & CO. (US) | 1982-07-06 | — | — | US | disclosed |
| US-4225502-A | CHELATING AGENTS | W. R. GRACE & CO. (US) | 1980-09-30 | — | — | US | disclosed |
| US-4152345-A | FOR USE IN PLATING BATHS, HORTICULTURE, STAIN REMOVAL | W. R. GRACE & CO. (US) | 1979-05-01 | — | — | US | disclosed |
| US-4069249-A | CHELATING AGENTS | W. R. GRACE & CO. (US) | 1978-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160184344-A1 | STIMULI RESPONSIVE COMPOSITIONS FOR IRON CHELATION | CD47, HBG2, HBG1 | AKR1B1 3457/4885MEN1 4608/4885KMT2A 3391/4885 |
| US-20170209400-A1 | METHODS AND TOPICAL FORMULATIONS FOR TREATING INFLAMMATION | MMP8, CXCL8, MMP1 | AKR1B1 3156/4885MEN1 3959/4885KMT2A 713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.