SCHEMBL369063

SCHEMBL369063

CC(=O)N(C)[Si](C)(C)N(C)C(C)=O.CC(=O)O[SiH2]OC(C)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL202677 0.81 LMNA (0.31)
SCHEMBL203137 0.75
SCHEMBL5612192 0.73
Methane SCHEMBL205249 0.72 ALDH1A1 (0.41)
SCHEMBL27805582 0.72 ALDH1A1 (0.41)
SCHEMBL22203995 0.70 ALDH1A1 (0.30)
SCHEMBL11259537 0.67 ALDH1A1 (0.32)
Butane SCHEMBL6454649 0.66 ALDH1A1 (0.41)
SCHEMBL5389414 0.65 ALDH1A1 (0.36)
SCHEMBL11579035 0.65 ALDH1A1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1866374-B1 ORGANOSILOXANE COMPOSITIONS DOW CORNING (US) 2016-06-08 EP disclosed
US-8524828-B2 Polymeric compositions DOW CORNING CORPORATION (US) 2013-09-03 US disclosed
EP-2265667-B1 POLYMERIC COMPOSITIONS DOW CORNING (US) 2013-01-16 EP disclosed
US-8344087-B2 Hydrosilylation cured organosiloxanes having diluent therein DOW CORNING CORPORATION (US) 2013-01-01 US disclosed
US-20120016063-A1 HYDROSILYLATION CURED ORGANOSILOXANES HAVING DILUENT THEREIN DOW SILICONES CORPORATION 2012-01-19 US disclosed
US-8067519-B2 Organosiloxane compositions DOW CORNING CORPORATION (US) 2011-11-29 US disclosed
US-20110198779-A1 Polymeric Compositions DOW CORNING EUROPE SA (BE) 2011-08-18 US disclosed
EP-2265667-A2 POLYMERIC COMPOSITIONS Dow Corning Corporation (US) 2010-12-29 EP disclosed
US-20100184883-A1 Extenders For Organosiloxane Compositions DOW CORNING LIMITED (GB) 2010-07-22 US disclosed
WO-2009127582-A2 POLYMERIC COMPOSITIONS DOW CORNING CORPORATION (US) 2009-10-22 WO disclosed
EP-2078065-A2 EXTENDERS FOR ORGANOSILOXANE COMPOSITIONS Dow Corning Corporation (US) 2009-07-15 EP disclosed
US-20080312367-A1 Organosiloxane Compositions DOW SILICONES CORPORATION 2008-12-18 US disclosed
WO-2008045417-A2 EXTENDERS FOR ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2008-04-17 WO disclosed