Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31414081 | 1.00 | GABRA1 (0.30) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL7207555 | 0.81 | GABRA1 (0.31) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL15329729 | 0.80 | GABRA1 (0.30) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL7211443 | 0.80 | GABRA1 (0.30) | GABRA1GABRB2 | |
| SCHEMBL16415244 | 0.77 | GABRA1 (0.34) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL8823402 | 0.75 | GABRA1 (0.31) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL3695192 | 0.74 | GABRA1 (0.30) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL30525908 | 0.74 | GABRA1 (0.30) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL937824 | 0.74 | GABRA1 (0.30) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL9421533 | 0.74 | GABRA1 (0.34) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741417-B2 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-06-22 | — | — | US | claimed |
| US-20070055028-A1 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-03-08 | — | — | US | claimed |
| EP-2064248-B1 | PREPARATION OF POLYMERIZATION CATALYST ACTIVATORS UTILIZING INDOLE-MODIFIED SILICA SUPPORTS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2018-10-10 | — | — | EP | disclosed |
| US-7741417-B2 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-06-22 | — | — | US | disclosed |
| EP-2064248-A1 | PREPARATION OF POLYMERIZATION CATALYST ACTIVATORS UTILIZING INDOLE-MODIFIED SILICA SUPPORTS | ExxonMobil Chemical Patents Inc. (US) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008027116-A1 | PREPARATION OF POLYMERIZATION CATALYST ACTIVATORS UTILIZING INDOLE-MODIFIED SILICA SUPPORTS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-03-06 | — | — | WO | disclosed |
| US-20070055028-A1 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-03-08 | — | — | US | disclosed |