Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30525908 | 1.00 | GABRA1 (0.30) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL6908071 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL1043012 | 0.81 | FAAH (0.31) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL6471000 | 0.80 | GABRA1 (0.30) | GABRA1GABRB2 | |
| Ethane SCHEMBL8629729 | 0.80 | GABRA1 (0.30) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL7216270 | 0.80 | GABRA1 (0.30) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL29710447 | 0.80 | GABRA1 (0.30) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL7719961 | 0.80 | GABRA1 (0.30) | GABRA1GABRB2 | |
| Propane SCHEMBL8628910 | 0.78 | — | — | |
| SCHEMBL16415244 | 0.77 | GABRA1 (0.34) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741417-B2 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-06-22 | — | — | US | claimed |
| US-20070055028-A1 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-03-08 | — | — | US | claimed |
| JP-3339864-B2 | — | — | 2002-10-28 | — | — | JP | claimed |
| EP-0760828-B1 | IMPROVED PROPYLENE COPOLYMER HEAT SEAL RESIN AND ARTICLES THEREFROM | EXXON CHEMICAL PATENTS INC (US) | 2001-05-23 | — | — | EP | claimed |
| US-5914376-A | Catalyst for the polymerization of olefins, process for the preparation thereof, and use thereof | TARGOR GMBH (DE) | 1999-06-22 | — | — | US | claimed |
| EP-0758355-B1 | APPLICATIONS OF ISOTACTIC POLYPROPYLENE, PROCESSES AND PRODUCTS THEREOF | EXXON CHEMICAL PATENTS INC (US) | 1998-12-09 | — | — | EP | claimed |
| EP-0758355-A1 | APPLICATIONS OF ISOTACTIC POLYPROPYLENE, PROCESSES AND PRODUCTS THEREOF | EXXON CHEMICAL PATENTS INC. (US) | 1997-02-19 | — | — | EP | claimed |
| US-5468440-A | Forming structure from polypropylene resin produced using metallocene catalyst, orienting structure by applying stress at temperature 20-35 degrees C. above Heat Distortion Test value of polypropylene | EXXON CHEMICAL PATENTS INC. (US) | 1995-11-21 | — | — | US | claimed |
| WO-1995030708-A1 | APPLICATIONS OF ISOTACTIC POLYPROPYLENE, PROCESSES AND PRODUCTS THEREOF | EXXON CHEMICAL PATENTS, INC. (US) | 1995-11-16 | — | — | WO | claimed |
| EP-2064248-B1 | PREPARATION OF POLYMERIZATION CATALYST ACTIVATORS UTILIZING INDOLE-MODIFIED SILICA SUPPORTS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2018-10-10 | — | — | EP | disclosed |
| US-8921489-B2 | Modified polyolefins with an exceptional profile of properties, process for preparation thereof and use thereof | EVONIK DEGUSSA GMBH (DE) | 2014-12-30 | — | — | US | disclosed |
| US-8846814-B2 | Use of polyolefins having isotactic structural elements in flooring materials | EVONIK DEGUSSA GMBH (DE) | 2014-09-30 | — | — | US | disclosed |
| US-8821971-B2 | Use of polyolefins having atactic structural elements in floor coverings | EVONIK DEGUSSA GMBH (DE) | 2014-09-02 | — | — | US | disclosed |
| US-8530582-B2 | Modified polyolefins with an exceptional profile of properties, process for preparation thereof and use thereof | EVONIK DEGUSSA GMBH (DE) | 2013-09-10 | — | — | US | disclosed |
| US-5578537-A | Olefin polymerization catalyst process for its preparation and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-26 | — | — | US | disclosed |
| WO-1995032235-A1 | IMPROVED PROPYLENE COPOLYMER HEAT SEAL RESIN AND ARTICLES THEREFROM | EXXON CHEMICAL PATENTS INC. (US) | 1995-11-30 | — | — | WO | disclosed |
| US-5468440-A | Forming structure from polypropylene resin produced using metallocene catalyst, orienting structure by applying stress at temperature 20-35 degrees C. above Heat Distortion Test value of polypropylene | EXXON CHEMICAL PATENTS INC. (US) | 1995-11-21 | — | — | US | disclosed |
| WO-1995030708-A1 | APPLICATIONS OF ISOTACTIC POLYPROPYLENE, PROCESSES AND PRODUCTS THEREOF | EXXON CHEMICAL PATENTS, INC. (US) | 1995-11-16 | — | — | WO | disclosed |
| EP-0578838-A1 | Olefin polymerization catalyst, process for its preparation, and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-19 | — | — | EP | disclosed |
| EP-0567952-A1 | Olefin polymerization catalyst, process for its preparation, and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |